[HTML][HTML] Radiation combined with immune checkpoint inhibitors for unresectable locally advanced non-small cell lung cancer: synergistic mechanisms, current state …

L Wu, Z Zhang, M Bai, Y Yan, J Yu, Y Xu - Cell Communication and …, 2023 - Springer
Until the advent of immune checkpoint inhibitors (ICIs), definitive radiotherapy (RT)
concurrently with chemotherapy was recommended for unresectable, locally advanced non …

[HTML][HTML] Efficacy and safety of consolidation durvalumab after chemoradiation therapy for stage III non-small-cell lung cancer: a systematic review, meta-analysis, and …

Y Zhang, Y Tian, L Zheng, X Sun, Z Zhao… - Frontiers in …, 2023 - frontiersin.org
Background: The current review aimed to pool real-world evidence on the efficacy and
toxicity of consolidation durvalumab for stage III unresectable non-small cell lung cancer …

Dosimetric predictors of pneumonitis in locally advanced non-small cell lung cancer patients treated with chemoradiation followed by durvalumab

RW Gao, CN Day, YY Nathan, A Bush, AC Amundson… - Lung Cancer, 2022 - Elsevier
Objectives The incidence and predictors of pneumonitis for patients with unresectable,
locally advanced non-small cell lung cancer (NSCLC) in the era of consolidation …

Real‐world experience of consolidation durvalumab after concurrent chemoradiotherapy in stage III non‐small cell lung cancer

Y Huang, JJ Zhao, YY Soon, A Wong… - Thoracic …, 2022 - Wiley Online Library
Background Durvalumab consolidation is associated with improved survival following
concurrent chemoradiotherapy (CCRT) in patients with stage III non‐small cell lung cancer …

Current challenges of unresectable stage III NSCLC: are we ready to break the glass ceiling of the PACIFIC trial?

J Remon, A Levy, P Singh… - Therapeutic …, 2022 - journals.sagepub.com
Consolidation anti-programmed death-ligand 1 has become a new standard of care in
unresectable stage III non-small cell lung cancer (NSCLC) following chemo-radiotherapy …

[HTML][HTML] Effect of sequence of radiotherapy combined with immunotherapy on the incidence of pneumonitis in patients with lung cancer: A systematic review and …

S Mi, N Liang, Y Zhang, Y Zhang, F Wang, L Qiao… - Clinical Lung Cancer, 2023 - Elsevier
Background With the widespread application of immune checkpoint inhibitor (ICI) combined
with radiotherapy (RT) for the treatment of lung cancer, increasing attention has been paid to …

Durvalumab after chemoradiotherapy in patients with stage III non-small-cell lung cancer: real-world outcomes versus clinical trial results

MV Verschueren, T Dijs, JL Gulikers, A Veelen… - …, 2023 - Future Medicine
Aim: We investigated the effectiveness of durvalumab post-concurrent CRT (cCRT) and post-
sequential CRT (sCRT) versus cCRT and sCRT alone and compared these outcomes with …

Elevated neutrophil‐to‐lymphocyte ratio (NLR) is associated with poorer progression‐free survival in unresectable stage III NSCLC treated with consolidation …

U Nindra, A Shahnam, S Stevens, A Pal… - Thoracic …, 2022 - Wiley Online Library
Sustained elevation in neutrophil‐to‐lymphocyte ratio (NLR) after initial chemoradiotherapy
(CRT) has been shown to correlate with worse prognosis in a number of solid organ …

[HTML][HTML] A propensity-matched retrospective comparative study with historical control to determine the real-world effectiveness of durvalumab after concurrent …

CK Park, N Jeon, HK Park, HJ Oh, YC Kim, HL Jeon… - Cancers, 2023 - mdpi.com
Simple Summary The PACIFIC trial demonstrated the survival benefits of durvalumab
consolidation (DC) in patients with unresectable stage III non–small cell lung cancer …

[HTML][HTML] Korean real-world data on patients with unresectable stage III NSCLC treated with durvalumab after chemoradiotherapy: PACIFIC-KR

CK Park, HJ Oh, YC Kim, YH Kim, SJ Ahn… - Journal of Thoracic …, 2023 - Elsevier
Introduction This study aimed to investigate real-world evidence for efficacy and safety of
durvalumab consolidation (DC) after chemoradiotherapy (CRT) in patients with unresectable …