PU. 1 eviction at lymphocyte-specific chromatin domains mediates glucocorticoid response in acute lymphoblastic leukemia
D Beck, H Cao, F Tian, Y Huang, M Jiang… - Nature …, 2024 - nature.com
The epigenetic landscape plays a critical role in cancer progression, yet its therapeutic
potential remains underexplored. Glucocorticoids are essential components of treatments for …
potential remains underexplored. Glucocorticoids are essential components of treatments for …
Pharmacological blockade of a pioneer transcription factor
K Cermakova, HC Hodges - Cancer Research, 2024 - aacrjournals.org
Cancers frequently co-opt lineage-specific transcription factors (TFs) utilized in normal
development to sustain proliferation. However, the effects of these TFs on tumor …
development to sustain proliferation. However, the effects of these TFs on tumor …