Lipid accumulation, inflammation, and oxidative stress are the most important causes of
muscle insulin resistance. The aim of this study was to investigate the single and combined …

Although the exact mechanism linking obesity to type 2 diabetes (T2D) remains unknown,
accumulating evidence suggests that low-grade chronic metabolic inflammation or …

Metformin is a highly effective medication for managing type 2 diabetes mellitus. Recent
studies have shown that it has significant therapeutic benefits in various organ systems …

Background Metabolic associated fatty liver disease (MAFLD) is a prevalent chronic liver
condition globally, currently lacking universally recognized therapeutic drugs, thereby …

Objectives: The aim of this study was to evaluate the effect of silymarin on liver enzyme
levels and serum lipid profiles in patients with Non-Alcoholic Fatty Liver Disease (NAFLD) …

Objectives: It has been reported that Metformin (MET), Resveratrol (RSV), and Quercetin
(QRS) possess anti-lipogenic effects. This study aimed to investigate the combined effects of …

Endotoxin, also identified as lipopolysaccharide (LPS), is considered the pathogenic factor
of septic shock triggered by Gram-negative bacteria and generates inflammatory responses …

The newest class of noncoding RNAs with distinctive characteristics is called circular RNAs
(circRNAs). These novel RNAs are more stable than other RNAs because they lack 5'and …

Objectives: Increasing evidence has demonstrated that oxidative stress plays a significant
role in the pathogenesis of muscle insulin resistance. The beneficial impacts of genistein …