[HTML][HTML] What are the current approaches to optimising antimicrobial dosing in the intensive care unit?

MG Chai, MO Cotta, MH Abdul-Aziz, JA Roberts - Pharmaceutics, 2020 - mdpi.com
Antimicrobial dosing in the intensive care unit (ICU) can be problematic due to various
challenges including unique physiological changes observed in critically ill patients and the …

[HTML][HTML] Optimizing antimicrobial therapy by integrating multi-omics with pharmacokinetic/pharmacodynamic models and precision dosing

HY Yow, K Govindaraju, AH Lim… - Frontiers in …, 2022 - frontiersin.org
In the era of “Bad Bugs, No Drugs,” optimizing antibiotic therapy against multi-drug resistant
(MDR) pathogens is crucial. Mathematical modelling has been employed to further optimize …

Gram-negative bacilli causing infections in an intensive care unit of a tertiary care hospital in Istanbul, Turkey

SS Akcay, A Inan, S Cevan, AN Ozaydın… - The Journal of Infection …, 2014 - jidc.org
Introduction: This study aimed to demonstrate the changing epidemiology of infecting
microorganisms and their long-term resistance profiles and to describe the microbiological …

Standard versus prolonged doripenem infusion for treatment of gram-negative infections

L Hsaiky, KP Murray, L Kokoska… - Annals of …, 2013 - journals.sagepub.com
BACKGROUND Doripenem is the most recently introduced carbapenem, with a broad
spectrum of antimicrobial activity. Preliminary data indicated that activity is optimized by …

Characterization of Carbapenem Nonsusceptible Pseudomonas aeruginosa in Denmark: A Nationwide, Prospective Study

F Hansen, HK Johansen, C Østergaard… - Microbial Drug …, 2014 - liebertpub.com
From January 1st 2011 through June 30th 2011, 116 nonreplicate, noncystic fibrosis-related
Pseudomonas aeruginosa isolates with reduced carbapenem susceptibility were collected …

[HTML][HTML] Recommendations for intra-abdominal infections consensus report

V Avkan-Oğuz, N Baykam, S Sökmen… - Turkish Journal of …, 2016 - ncbi.nlm.nih.gov
Guidelines include the recommendations of experts from various specialties within a topic in
consideration of data specific to each country. However, to date there has not been a …

重症监护室术后先天性心脏病患儿院内感染细菌分布及耐药性分析

孙跃玉, 陈炫炜, 郭予雄, 何少茹 - 实用儿科临床杂志, 2012 - cqvip.com
目的分析术后先天性心脏病(先心) 患儿发生院内感染后分离所得的所有病原菌,
了解心脏病术后患儿在PICU 感染的病原菌分布特点和耐药状况, 为治疗提供依据. 方法2009 …

Karbapenem dirençli enterobacteriacae enfeksiyonları: Risk faktörleri

F Eser, GR Yılmaz, R Güner, ZK Tufan, T Güven… - Akdeniz Tıp …, 2018 - dergipark.org.tr
Amaç: Enterobacteriaceae ailesi ve özellikle Klebsiella pneumoniae tedavisi zor ve artan
direnç durumu ile birlikte tedavi seçenekleri daha da sınırlı hale gelen enfeksiyon …

[PDF][PDF] POLİKLİNİK HASTALARININ İDRAR KÜLTÜRLERİNDEN İZOLE EDİLEN ESCHERICHIA COLI VE KLEBSIELLA PNEUMONIAE SUŞLARININ GENİŞLEMİŞ …

F TEMOÇİN, H KÖSE - ANKEM Derg, 2018 - researchgate.net
ÖZ Üriner sistem infeksiyonları (ÜSİ), infeksiyon hastalıkları pratiğinde en sık karşılaşılan
hastalıklardan biridir. Komplike olmayan ÜSİ'lerin% 75-95'inden Gram negatif bakteriler …

[PDF][PDF] Carbapenem-resistant enterobacteriaceae

F Eser - Medical Journal of Islamic World Academy of …, 2017 - jag.journalagent.com
Carbapenem-resistant Enterobacteriaceae (CRE) is a bacterial family difficult to treat with
high resistance rates to broad-spectrum antibiotics. Patients following up in long-term-care …