Benefiting from the impressive increase in fundamental knowledge, the last 20 years have
shown a continuous burst of new ideas and consequently a plethora of new catalytic …

The radical-involved 1, 2-difunctionalization of alkenes has developed into a robust tool for
preparation of complex organic molecules. Despite significant advances in this area, the …

The area of catalysis of radical reactions has recently flourished. Various reaction conditions
have been discovered and explained in terms of catalytic cycles. These cycles rarely stand …

1. INTRODUCTION This review article is concerned with the use of compounds 1 and 2
(Figure 1) as effective and very versatile reagents for trifluoromethylation reactions of a …

The C–O bond is ubiquitous in biologically active molecules, pharmaceutical agents, and
functional materials, thereby making it an important functional group. Consequently, the …

Fluorine has emerged as a “magic element” in medicinal chemistry, crop, and materials
science. 1 Although fluorine is the most abundant halogen in the earth's crust, it is contained …

Over the past decade, the most significant, conceptual advances in the field of fluorination
were enabled most prominently by organo‐and transition‐metal catalysis. The most …

In the last few years, the efficient introduction of trifluoromethyl groups in organic molecules
has become a major research focus. This review highlights the recent developments …

Direct difunctionalization of simple alkenes, the incorporation of two functional groups onto a
carbon–carbon double bond, is of particular interest to the chemical community owing to its …

The trifluoromethyl group is found in many synthetic bioactive compounds, and the
difunctionalization of a C C bond, as a powerful strategy for the construction of compounds …