Alzheimer's disease (AD) is a severe neurodegenerative disorder and the most common
type of dementia in the elderly. The clinical symptoms of AD include a progressive loss of …

Alzheimer's disease (AD) is a progressive neurological illness that causes dementia mainly
in the elderly. The challenging obstacles related to AD has freaked global healthcare system …

Neurodegenerative Diseases (NDs) are progressive multifactorial neurological pathologies
related to neuronal impairment and functional loss from different brain regions. Currently, no …

Quinazolines are considered as a promising class of bioactive heterocyclic compounds with
broad properties. Particularly, the quinazoline scaffold has an impressive role in the design …

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that effects 50 million
people worldwide. In this review, AD pathology and the development of novel therapeutic …

Alzheimer's disease (AD) is an irreversible, progressive neurological disorder characterized
by amyloid plaques, hyperphosphorylated tau protein (hyper p-tau), neuronal damage …

Neurodegenerative diseases (ND), including Alzheimer's (AD) and Parkinson's Disease
(PD), are becoming increasingly more common and are recognized as a social problem in …

Alzheimer's disease (AD) is a complex neurological disorder with diverse underlying
pathological processes. Several lines of evidence suggest that BACE1 is a key enzyme in …

The complex pathogenesis of Alzheimer's disease (AD) requires using multi-target ligands
(MTLs) for disease management. We synthesized, characterized and evaluated a series of …

A library of twelve quinazoline-triazole hybrid compounds were designed, synthesized and
evaluated as a novel class of acetylcholinesterase inhibitors to treat Alzheimer's disease …