Environmental risks of disposable face masks during the pandemic of COVID-19: Challenges and management

B Li, Y Huang, D Guo, Y Liu, Z Liu, JC Han… - Science of the Total …, 2022 - Elsevier
Since the COVID-19 outbreak in early 2020, face mask (FM) has been recognized as an
effective measure to reduce the infection, increasing its consumption across the world …

Unraveling the complex genetics of neural tube defects: From biological models to human genomics and back

P Wolujewicz, JW Steele, JA Kaltschmidt, RH Finnell… - Genesis, 2021 - Wiley Online Library
Neural tube defects (NTDs) are a classic example of preventable birth defects for which
there is a proven‐effective intervention, folic acid (FA); however, further methods of …

A Shared Pathogenic Mechanism for Valproic Acid and SHROOM3 Knockout in a Brain Organoid Model of Neural Tube Defects

TN Takla, J Luo, R Sudyk, J Huang, JC Walker… - Cells, 2023 - mdpi.com
Neural tube defects (NTDs), including anencephaly and spina bifida, are common major
malformations of fetal development resulting from incomplete closure of the neural tube …

Overview of neural tube defects: gene–environment interactions, preventative approaches and future perspectives

J Isaković, I Šimunić, D Jagečić, V Hribljan, D Mitrečić - Biomedicines, 2022 - mdpi.com
Neural tube defects (NTDs) are the second most common congenital malformations of
humans, characterized by impaired development of the central nervous system. Even …

Closing in on mechanisms of open neural tube defects

S Lee, JG Gleeson - Trends in neurosciences, 2020 - cell.com
Neural tube defects (NTDs) represent a failure of the neural plate to complete the
developmental transition to a neural tube. NTDs are the most common birth anomaly of the …

Micronutrient imbalance and common phenotypes in neural tube defects

AD Kakebeen, L Niswander - genesis, 2021 - Wiley Online Library
Neural tube defects (NTDs) are among the most common birth defects, with a prevalence of
close to 19 per 10,000 births worldwide. The etiology of NTDs is complex involving the …

Advantages of CRISPR-Cas9 combined organoid model in the study of congenital nervous system malformations

L Xiaoshuai, W Qiushi, W Rui - Frontiers in Bioengineering and …, 2022 - frontiersin.org
In the past 10 years, gene-editing and organoid culture have completely changed the
process of biology. Congenital nervous system malformations are difficult to study due to …

Progress in modeling neural tube development and defects by organoid reconstruction

P Li, Y Chen - Neuroscience Bulletin, 2022 - Springer
It is clear that organoids are useful for studying the structure as well as the functions of
organs and tissues; they are able to simulate cell-to-cell interactions, symmetrical and …

Genome‐wide analysis of spina bifida risk variants in a case–control study from Bangladesh

G Tindula, B Issac, SK Mukherjee… - Birth Defects …, 2024 - Wiley Online Library
Background Human studies of genetic risk factors for neural tube defects, severe birth
defects associated with long‐term health consequences in surviving children, have …

Identification of the key regulators of spina bifida through graph-theoretical approach

N Tamkeen, SY AlOmar, SAM Alqahtani… - Frontiers in …, 2021 - frontiersin.org
Spina Bifida (SB) is a congenital spinal cord malformation. Efforts to discern the key
regulators (KRs) of the SB protein-protein interaction (PPI) network are requisite for …