Current clinical practices focus on a small number of biochemical directly related to the
pathophysiology with patients and thus only describe a very limited metabolome of a patient …

Trimethylamine (TMA) is a tertiary amine with a characteristic fishy odour. It is synthesised
from dietary constituents, including choline, L-carnitine, betaine and lecithin by the action of …

Coronary heart disease (CHD) is top risk factor for health in modern society, causing high
mortality rate each year. However, there is no reliable way for early diagnosis and …

In this work, the variations in the metabolic profile of blood plasma from lung cancer patients
and healthy controls were investigated through NMR-based metabonomics, to assess the …

Rationale and Objectives To retrospectively evaluate the diagnostic performance of texture
analysis (TA) for the discrimination of angiomyolipoma (AML) with minimal fat, clear cell …

Chronic obstructive pulmonary disease (COPD) and lung cancer are widespread lung
diseases. Cigarette smoking is a high risk factor for both the diseases. COPD may increase …

A LC− MS based method, which utilizes both reversed-performance (RP) chromatography
and hydrophilic interaction chromatography (HILIC) separations, has been carried out in …

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world.
However, current biomarkers that discriminate HCC from liver cirrhosis (LC) are important …

The first discovery of metabolic changes in cancer occurred almost a century ago. While the
genetic underpinnings of cancer have dominated its study since then, altered metabolism …

Lung cancer (LC) is responsible for most cancer deaths. One of the main factors contributing
to the lethality of this disease is the fact that a large proportion of patients are diagnosed at …