Prognostic significance of KIF11 and KIF14 expression in pancreatic adenocarcinoma

A Klimaszewska-Wiśniewska, I Neska-Długosz… - Cancers, 2021 - mdpi.com
Simple Summary Prognostic markers for survival stratification of patients with pancreatic
adenocarcinoma (PAC) are missing yet. Therefore, the primary aim of this study was to …

Comprehensive analysis of expression, prognostic value, and immune infiltration for ubiquitination-related FBXOs in pancreatic ductal adenocarcinoma

Y Zhang, Q Liu, M Cui, M Wang, S Hua, J Gao… - Frontiers in …, 2022 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is one of the most refractory human
malignancies. F-box only proteins (FBXO) are the core components of SKP1-cullin 1-F-box …

Prognostic significance of MATR3 in stage I and II non-small cell lung cancer patients

J Durślewicz, A Klimaszewska-Wiśniewska… - Journal of Cancer …, 2022 - Springer
Abstract Purpose Matrin 3 (MATR3) is a nuclear matrix protein involved in mRNA
stabilization, nuclear retention of hyper-edited RNAs, and RNA splicing. The role of MATR3 …

Ribonucleotide reductase M2 subunit silencing suppresses tumorigenesis in pancreatic cancer via inactivation of PI3K/AKT/mTOR pathway

J Shan, Z Wang, Q Mo, J Long, Y Fan, L Cheng… - Pancreatology, 2022 - Elsevier
Abstract Background/objectives Ribonucleotide Reductase M2 subunit (RRM2) is elevated
in pancreatic cancer and involved in DNA synthesis and cell proliferation. But its specific …

[HTML][HTML] A comprehensive analysis of the prognostic, immunological and diagnostic role of CCNF in pan-cancer

X Gao, H Bu, J Ge, X Gao, Y Wang, Z Zhang… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Cyclin F (CCNF) represents a pivotal constituent within the family of cell cycle
proteins, which also belongs to the F-box protein family and acts as a critical regulatory …

High RRM2 expression has poor prognosis in specific types of breast cancer

S Shi, Y Zhang, T Wang - PLoS One, 2022 - journals.plos.org
Background RRM2 plays an important role in different malignant tumors, but there are few
studies in breast cancer. Public databases were used to analyze the expression of RRM2 in …

Overexpression of cyclin F/CCNF as an independent prognostic factor for poor survival in clear cell renal cell carcinoma

M Kwiatkowski, A Krajewski, J Durślewicz… - Scientific Reports, 2024 - nature.com
Cyclin F (encoded by CCNF gene) has been reported to be implicated in the pathobiology of
several human cancers. However, its potential clinical significance in clear cell renal cell …

Pan-cancer analysis combined with experiments explores the oncogenic role of spindle apparatus coiled-coil protein 1 (SPDL1)

P Song, D Wusiman, F Li, X Wu, L Guo, W Li… - Cancer cell …, 2022 - Springer
Background The function of spindle apparatus coiled-coil protein 1 (SPDL1) as a cancer-
promoting gene has been reported in a number of studies. However, the pan-cancer …

Identification of a somatic mutation-derived long non-coding RNA signatures of genomic instability in renal cell carcinoma

X Fang, X Liu, L Lu, G Liu - Frontiers in Oncology, 2021 - frontiersin.org
Background Renal cell carcinoma (RCC) is a malignant tumor with high morbidity and
mortality. It is characterized by a large number of somatic mutations and genomic instability …

Prognostic significance of TLR2, SMAD3 and localization-dependent SATB1 in stage I and II non–small-cell lung cancer patients

J Durślewicz, A Klimaszewska-Wiśniewska… - Cancer …, 2021 - journals.sagepub.com
This study aimed to explore the prognostic value of SATB1, SMAD3, and TLR2 expression in
non–small-cell lung carcinoma patients with clinical stages I-II. To investigate, we evaluated …