Polymeric in situ forming depots have emerged as highly promising drug delivery systems
for long-acting applications. Their effectiveness is attributed to essential characteristics such …

Adherence to daily oral antiretroviral therapy (ART) is a barrier to both treatment and
prevention of human immunodeficiency virus (HIV) infection. To overcome limitations of life …

The success of long-acting (LA) drug delivery systems (DDSs) is linked to their
biocompatible polymers. These are used for extended therapeutic release. For treatment or …

Only condoms are proven to protect against both HIV and unplanned pregnancy, however,
poor user acceptability and lack of partner cooperation impede effectiveness. We developed …

Breast cancer is among the most prevalent tumors worldwide. In this study, in-situ forming
implants (ISFIs) containing rosuvastatin calcium were prepared using three types of poly (D …

Pre-exposure prophylaxis (PrEP) has revolutionized the human immunodeficiency virus
(HIV) prevention strategy during the past 15 years. Despite of the fact that people living with …

Despite the success of current antiretroviral therapy and PrEP with one-pill, once-daily
regimens, there is a continuing need for new formulations, investigational agents, and novel …

To succeed in ending the HIV epidemic in the United States, the Centers for Disease Control
and Prevention (CDC) focuses on delivering combinations of scientifically proven, cost …

HIV continues to affect millions of men and women worldwide. The development of long-
acting injectables for HIV prevention can overcome adherence challenges with daily oral …

Since the advent of highly active antiretroviral therapy, many efforts have been made to
broaden the spectrum of possible regimens. Long-acting antiretrovirals, are particularly …