Chemokines

KJ Laing, CJ Secombes - Developmental & Comparative Immunology, 2004 - Elsevier
Chemokines are small proteins that control cellular migration. An extensive family of these
molecules has been described in mammals containing nearly 50 members. Within this …

Viral mimicry of cytokines, chemokines and their receptors

A Alcami - Nature Reviews Immunology, 2003 - nature.com
Viruses have evolved elegant mechanisms to evade detection and destruction by the host
immune system. One of the evasion strategies that have been adopted by large DNA viruses …

DNAWorks: an automated method for designing oligonucleotides for PCR-based gene synthesis

DM Hoover, J Lubkowski - Nucleic acids research, 2002 - academic.oup.com
The availability of sequences of entire genomes has dramatically increased the number of
protein targets, many of which will need to be overexpressed in cells other than the original …

Marek's disease virus: from miasma to model

N Osterrieder, JP Kamil, D Schumacher… - Nature Reviews …, 2006 - nature.com
Marek's disease virus (MDV) is an oncogenic herpesvirus that causes various clinical
syndromes in its natural host, the chicken. MDV has long been of interest as a model …

Marek's disease in chickens: a review with focus on immunology

N Boodhoo, A Gurung, S Sharif, S Behboudi - Veterinary research, 2016 - Springer
Abstract Marek's disease (MD), caused by Marek's disease virus (MDV), is a commercially
important neoplastic disease of poultry which is only controlled by mass vaccination …

Marek's disease virus-encoded Meq gene is involved in transformation of lymphocytes but is dispensable for replication

B Lupiani, LF Lee, X Cui, I Gimeno… - Proceedings of the …, 2004 - National Acad Sciences
Marek's disease virus (MDV) causes an acute lymphoproliferative disease in chickens,
resulting in T cell lymphomas in visceral organs and peripheral nerves. Earlier studies have …

Defining the origins and evolution of the chemokine/chemokine receptor system

ME DeVries, AA Kelvin, L Xu, L Ran… - The Journal of …, 2006 - journals.aai.org
The chemokine system has a critical role in mammalian immunity, but the evolutionary
history of chemokines and chemokine receptors are ill-defined. We used comparative whole …

Evolution of Marek's disease–a paradigm for incessant race between the pathogen and the host

V Nair - The Veterinary Journal, 2005 - Elsevier
Marek's disease (MD) is a highly contagious lymphoproliferative disease of poultry caused
by the oncogenic herpesvirus designated Marek's disease virus (MDV). MD has a worldwide …

Latest insights into Marek's disease virus pathogenesis and tumorigenesis

LD Bertzbach, AM Conradie, Y You, BB Kaufer - Cancers, 2020 - mdpi.com
Marek's disease virus (MDV) infects chickens and causes one of the most frequent cancers
in animals. Over 100 years of research on this oncogenic alphaherpesvirus has led to a …

Differential cytokine responses following Marek's disease virus infection of chickens differing in resistance to Marek's disease

P Kaiser, G Underwood, F Davison - Journal of virology, 2003 - Am Soc Microbiol
The production of cytokine mRNAs, in addition to viral DNA, was quantified by real-time
quantitative reverse transcription-PCR (RT-PCR)(cytokines) or PCR (virus) in splenocytes …