Parathyroid hormone-related protein: biochemistry and molecular biology

TJ Martin, JM Moseley, MT Gillespie - Critical reviews in …, 1991 - Taylor & Francis
This article critically reviews the current state of knowledge regarding the recently identified
and cloned novel hormone parathyroid hormone-related protein (PTHrP). PTHrP is …

Neuroregulation of the neuroendocrine compartment of the liver

T Roskams, D Cassiman, R De Vos… - … Record Part A …, 2004 - Wiley Online Library
Liver progenitor cells as well as hepatic stellate cells have neuroendocrine features.
Progenitor cells express chromogranin‐A and neural cell adhesion molecule, parathyroid …

Parathyroid hormone-related protein purified from a human lung cancer cell line.

JM Moseley, M Kubota… - Proceedings of the …, 1987 - National Acad Sciences
A protein with biological activities similar to parathyroid hormone (PTH) has been purified
from serum-free culture medium obtained from a human lung cancer cell line (BEN). A major …

Parathyroid hormonelike protein from human renal carcinoma cells. Structural and functional homology with parathyroid hormone.

GJ Strewler, PH Stern, JW Jacobs… - The Journal of …, 1987 - Am Soc Clin Investig
A variety of solid tumors secrete proteins that are immunochemically distinct from
parathyroid hormone (PTH) but activate PTH-responsive adenylate cyclase. Such PTH-like …

[HTML][HTML] Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of …

WJ Burtis, T Wu, C Bunch, JJ Wysolmerski… - Journal of Biological …, 1987 - Elsevier
Humoral hypercalcemia of malignancy is a common paraneoplastic syndrome which is
characterized by hypercalcemia resulting from secretion by tumors of a circulating bone …

Effects of a synthetic peptide of a parathyroid hormone-related protein on calcium homeostasis, renal tubular calcium reabsorption, and bone metabolism in vivo and …

AJ Yates, GE Gutierrez, P Smolens… - The Journal of …, 1988 - Am Soc Clin Investig
A synthetic peptide corresponding to the first 34 amino acids of the parathyroid hormone-
related protein (PTH-rP) produced by a human tumor associated with hypercalcemia was …

The parathyroid hormone-like peptide associated with humoral hypercalcemia of malignancy and parathyroid hormone bind to the same receptor on the plasma …

H Jüppner, AB Abou-Samra, S Uneno, WX Gu… - Journal of Biological …, 1988 - ASBMB
[Tyr36] human adenylate cyclase stimulating peptide (1-36)-NH2, an amino-terminal analog
of a tumor peptide which is associated with hypercalcemia of malignancy, and [Nle8, Nle18 …

An amino-terminal fragment of urokinase isolated from a prostate cancer cell line (PC-3) is mitogenic for osteoblast-like cells

SA Rabbani, J Desjardins, AW Bell, D Banville… - Biochemical and …, 1990 - Elsevier
A peptide mitogen for cultured osteoblast-like cells was purified from aerum-free conditioned
culture medium of a human prostatic cancer cell line, PC-3. Based on amino acid …

Parathyroid hormone-like peptide in normal and neoplastic human endocrine tissues

SL ASA, J HENDERSON, D GOLTZMAN… - The Journal of …, 1990 - academic.oup.com
PTH-like peptide (PLP) is produced by tumors commonly associated with hypercalcemia as
well as nonneoplastic tissues and several endocrine glands and tumors. To characterize the …

Parathyroid hormone-related protein

JM Moseley, MT Gillespie… - Critical reviews in clinical …, 1995 - Taylor & Francis
We review the current state of knowledge of the molecular properties and actions of
parathyroid hormone-related protein (PTHrP) both in cancer patients and in normal …