Cancer immunotherapy is quickly growing to be the fourth most important cancer therapy,
after surgery, radiation therapy, and chemotherapy. Immunotherapy is the most promising …

While breast cancer has not been considered a cancer amenable to immunotherapeutic
approaches, recent studies have demonstrated evidence of significant immune cell …

The vast majority of cancer-related deaths are due to metastasis, a process that requires
evasion of the host immune system. In addition, a significant percentage of cancer patients …

The aryl hydrocarbon receptor (AhR) is a ligand-operated transcription factor originally
recognized as the mediator of the toxicity of dioxins. AhR is presumed to have evolved from …

Neuroinflammation driven altered neurochemical milieu have been reported to play a
significant role in pathogenesis of comorbid depression in epilepsy. Most of the antiepileptic …

Abstract Indoleamine‐2, 3 dioxygenase 1 (IDO1) has emerged as a central regulator of
immune responses in both normal and disease biology. Due to its established role in …

Objective: Indoleamin-2, 3-dioxygenase-1 (IDO) has been identified as a checkpoint protein
involved in generating the immunosuppressive tumor microenvironment that supports tumor …

Immunotherapy-based combinations: current status and perspec... : Current Opinion in
Oncology Immunotherapy-based combinations: current status and perspectives : Current …

Emerging data is suggesting that the process of dendritic cell (DC) tolerization is an
important step in tumorigenesis. Our understanding of the networks within the tumor …

Aberrant Wnt signaling is a hallmark of many cancer types such as colon cancer. However,
the effect of altered Wnt signaling is not only restricted to cancer cells but also dynamically …