Inflammation is an adaptive response in pursuit of homeostasis reestablishment triggered by
harmful conditions or stimuli, such as an infection or tissue damage. Liver diseases cause …

Coronavirus disease 2019 (COVID-19) has caused an unprecedented global crisis and
continues to threaten public health. The etiological agent of this devastating pandemic …

INTRODUCTION In all eukaryotic cells, lipid droplets (LDs) store and supply essential lipids
to produce signaling molecules, membrane building blocks, and metabolic energy. The LD …

Nonalcoholic steatohepatitis (NASH) is emerging as a leading cause of chronic liver
disease. However, therapeutic options are limited by incomplete understanding of the …

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causing the COVID-19
respiratory disease pandemic utilizes unique 2′-o-methyltransferase (2′-O-MTase) …

Background & Aims Activation of Kupffer cells and recruitment of monocytes are key events
in fibrogenesis. These cells release soluble mediators which induce the activation of hepatic …

Background Early diagnosis is crucial for patients with pancreatic ductal adenocarcinoma
(PDAC). The AXL receptor tyrosine kinase is proteolytically processed releasing a soluble …

Nonalcoholic steatohepatitis, one of the most common chronic liver diseases, is a
progressive form of nonalcoholic fatty liver disease accompanied by the development of liver …

The TAM receptor family of TYRO3, AXL and MERTK regulates tissue and immune
homeostasis. Aberrant TAM receptor signalling has been linked to a range of diseases …

Transforming growth factor β (TGF-β) is a multifunctional cytokine regulating homeostasis
and immune responses in adult animals and humans. Aberrant and overactive TGF-β …