Proteomics of the Heart
OA Karpov, A Stotland, K Raedschelders… - Physiological …, 2024 - journals.physiology.org
Mass spectrometry-based proteomics is a sophisticated identification tool specializing in
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …
Using Omics to Identify Novel Therapeutic Targets in Heart Failure
C Lteif, Y Huang, LA Guerra… - Circulation: Genomic …, 2024 - Am Heart Assoc
Omics refers to the measurement and analysis of the totality of molecules or biological
processes involved within an organism. Examples of omics data include genomics …
processes involved within an organism. Examples of omics data include genomics …
[HTML][HTML] CardiOmics signatures reveal therapeutically actionable targets and drugs for cardiovascular diseases
MJ Ramos-Medina, G Echeverría-Garcés… - Heliyon, 2024 - cell.com
Cardiovascular diseases are the leading cause of death worldwide, with heart failure being
a complex condition that affects millions of individuals. Single-nucleus RNA sequencing has …
a complex condition that affects millions of individuals. Single-nucleus RNA sequencing has …
Characterization of genomic regions escaping epigenetic reprogramming in sheep
CU Braz, MM Passamonti… - Environmental Epigenetics, 2024 - academic.oup.com
The mammalian genome undergoes two global epigenetic reprogramming events during
the establishment of primordial germ cells and in the pre-implantation embryo after …
the establishment of primordial germ cells and in the pre-implantation embryo after …
[HTML][HTML] Mst4, a novel cardiac STRIPAK complex–associated kinase, regulates cardiomyocyte growth and survival and is upregulated in human cardiomyopathy
M Eden, M Leye, J Hahn, E Heilein… - Journal of Biological …, 2024 - ASBMB
Myocardial failure is associated with adverse remodeling, including loss of cardiomyocytes,
hypertrophy, and alterations in cell–cell contacts. Striatin-interacting phosphatase and …
hypertrophy, and alterations in cell–cell contacts. Striatin-interacting phosphatase and …
Multi‐omic analyses and network biology in cardiovascular disease
CJ Reitz, U Kuzmanov, AO Gramolini - Proteomics, 2023 - Wiley Online Library
Heart disease remains a leading cause of death in North America and worldwide. Despite
advances in therapies, the chronic nature of cardiovascular diseases ultimately results in …
advances in therapies, the chronic nature of cardiovascular diseases ultimately results in …
Cardiac stress leads to regulation of Filamin C dimerisation via an ancient phosphorylation-modulated interaction with HSPB7
Z Wang, G Cao, MP Collier, X Qiu… - bioRxiv, 2024 - biorxiv.org
The biomechanical properties and responses of tissues underpin a variety of physiological
functions and pathologies. In striated muscle, the actin-binding protein filamin C (FLNC) is a …
functions and pathologies. In striated muscle, the actin-binding protein filamin C (FLNC) is a …
Identification of candidate biomarkers and pathways associated with multiple sclerosis using bioinformatics and next generation sequencing data analysis
BM Vastrad, CM Vastrad - bioRxiv, 2023 - biorxiv.org
Multiple sclerosis (MS) is the main reason for disability caused by autoimmunity. However,
effective biomarkers for MS have not been identified. This study explored the molecular …
effective biomarkers for MS have not been identified. This study explored the molecular …
[PDF][PDF] Multi-omic analyses and network biology in cardiovascular
CJ Reitz, U Kuzmanov, AO Gramolini - 2023 - researchgate.net
Heart disease remains a leading cause of death in North America and worldwide. Despite
advances in therapies, the chronic nature of cardiovascular diseases ultimately results in …
advances in therapies, the chronic nature of cardiovascular diseases ultimately results in …