Tryptophan metabolism in depression: a narrative review with a focus on serotonin and kynurenine pathways
AS Correia, N Vale - International journal of molecular sciences, 2022 - mdpi.com
Depression is a common and serious disorder, characterized by symptoms like anhedonia,
lack of energy, sad mood, low appetite, and sleep disturbances. This disease is very …
lack of energy, sad mood, low appetite, and sleep disturbances. This disease is very …
Mechanisms underlying neurodegenerative disorders and potential neuroprotective activity of agrifood by-products
C Angeloni, M Malaguti, C Prata, M Freschi… - Antioxidants, 2022 - mdpi.com
Neurodegenerative diseases, characterized by progressive loss in selected areas of the
nervous system, are becoming increasingly prevalent worldwide due to an aging population …
nervous system, are becoming increasingly prevalent worldwide due to an aging population …
Natural products inhibitors of monoamine oxidases—Potential new drug leads for neuroprotection, neurological disorders, and neuroblastoma
Monoamine oxidase inhibitors (MAOIs) are an important class of drugs prescribed for
treatment of depression and other neurological disorders. Evidence has suggested that …
treatment of depression and other neurological disorders. Evidence has suggested that …
Mechanisms of dopamine oxidation and Parkinson's disease
J Segura-Aguilar, I Paris - Handbook of neurotoxicity, 2022 - Springer
Dopamine's ability to oxidize to aminochrome explains why this molecule may be a
neurotoxic compound that induces toxicity in both cell lines and animal models …
neurotoxic compound that induces toxicity in both cell lines and animal models …
Sympathetic Nervous System and Atherosclerosis
Atherosclerosis is characterized by the narrowing of the arterial lumen due to subendothelial
lipid accumulation, with hypercholesterolemia being a major risk factor. Despite the recent …
lipid accumulation, with hypercholesterolemia being a major risk factor. Despite the recent …
Corpora cavernosa fibroblasts mediate penile erection
EL Guimaraes, DO Dias, WF Hau, A Julien, D Holl… - Science, 2024 - science.org
Penile erection is mediated by the corpora cavernosa, a trabecular-like vascular bed that
enlarges upon vasodilation, but its regulation is not completely understood. Here, we show …
enlarges upon vasodilation, but its regulation is not completely understood. Here, we show …
The role of pharmacogenetics in personalizing the antidepressant and anxiolytic therapy
M Radosavljevic, D Svob Strac, J Jancic, J Samardzic - Genes, 2023 - mdpi.com
Pharmacotherapy for neuropsychiatric disorders, such as anxiety and depression, has been
characterized by significant inter-individual variability in drug response and the development …
characterized by significant inter-individual variability in drug response and the development …
Anoectochilus roxburghii flavonoids extract ameliorated the memory decline and reduced neuron apoptosis via modulating SIRT1 signaling pathway in senescent …
Z Zeng, C Chen, Y SiTu, Z Shen, Y Chen… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Anoectochilus roxburghii (A. roxburghii) is a precious herb
and folk medicine in many Asian countries. It has been used traditionally to treat diabetes …
and folk medicine in many Asian countries. It has been used traditionally to treat diabetes …
Resveratrol-based compounds and neurodegeneration: Recent insight in multitarget therapy
M Fantacuzzi, R Amoroso, S Carradori… - European Journal of …, 2022 - Elsevier
Neurodegenerative diseases (NDs) are characterized by gradual and progressive loss of
selectively vulnerable populations of neurons, including death of neurons in different …
selectively vulnerable populations of neurons, including death of neurons in different …
Neurotoxic and behavioral deficit in Drosophila melanogaster co-exposed to rotenone and iron
Exposure to environmental toxicants has been linked with the onset of different
neurodegenerative diseases in animals and humans. Here, we evaluated the toxic effects of …
neurodegenerative diseases in animals and humans. Here, we evaluated the toxic effects of …