As the population ages, the economic and societal impacts of neurodegenerative and
neuropsychiatric disorders are expected to rise sharply. Like dementia, late-life depressive …

Depression is a major contributor to the global burden of disease and disability, yet it is
poorly understood. Here we review data supporting a novel theoretical model for the biology …

Background Vascular depression is regarded as a subtype of late-life depression
characterized by a distinct clinical presentation and an association with cerebrovascular …

In the mammalian cortex, neurons and glia form a patterned structure across six layers
whose complex cytoarchitectonic arrangement is likely to contribute to cognition. We …

Background: The impact of dietary flavonoid intakes on risk of depression is unclear.
Objective: We prospectively examined associations between estimated habitual intakes of …

Background and Purpose: Intracerebral hemorrhage (ICH) is an acute manifestation of
cerebral small vessel disease (CSVD), usually cerebral amyloid angiopathy or hypertensive …

Objectives: The objectives of this study were to determine the effects of the novel Buddhism-
based walking meditation (BWM) and the traditional walking exercise (TWE) on depression …

Background White matter hyperintensities (WMH) lesions on T2/FLAIR brain MRI are
frequently seen in healthy elderly people. Whether these radiological lesions correspond to …

Cerebral ischemia contributes to significant disabilities worldwide, impairing cognitive
function and motor coordination in affected individuals. Stroke has severe …

Depression in older individuals is a common complex mood disorder with high comorbidity
of both psychiatric and physical diseases, associated with high disability, cognitive decline …