Advances in organocatalyzed synthesis of organic compounds
The recent advancements in utilizing organocatalysts for the synthesis of organic
compounds have been described in this review by focusing on their simplicity, effectiveness …
compounds have been described in this review by focusing on their simplicity, effectiveness …
Vanillin: a promising biosourced building block for the preparation of various heterocycles
D Gendron - Frontiers in Chemistry, 2022 - frontiersin.org
The preparation of heterocyclic compounds often involves the use of petroleum-based or
non-renewable sources. Considering the actual societal and environmental awareness …
non-renewable sources. Considering the actual societal and environmental awareness …
Design, synthesis, and pharmacological evaluation of embelin–aryl/alkyl amine hybrids as orally bioavailable blood–brain barrier permeable multitargeted agents with …
VK Nuthakki, S Choudhary, CN Reddy… - ACS chemical …, 2023 - ACS Publications
The complex and multifaceted nature of Alzheimer's disease has brought about a pressing
demand to develop ligands targeting multiple pathways to combat its outrageous …
demand to develop ligands targeting multiple pathways to combat its outrageous …
Quinoxalinone substituted pyrrolizine (4h)-induced dual inhibition of AKT and ERK instigates apoptosis in breast and colorectal cancer by modulating mitochondrial …
T Amin, RP Sharma, KB Mir, N Slathia… - European Journal of …, 2023 - Elsevier
AKT and ERK 1/2 play a pivotal role in cancer cell survival, proliferation, migration, and
angiogenesis. Therefore, AKT and ERK 1/2 are considered crucial targets for cancer …
angiogenesis. Therefore, AKT and ERK 1/2 are considered crucial targets for cancer …
An Energetic and Topological Approach to Understanding the Interplay of Noncovalent Interactions in a Series of Crystalline Spiropyrrolizine Compounds
Synthesis of quinoline-containing spiropyrrolizine was achieved via a 1, 3-dipolar
cycloaddition reaction of azomethine ylide (generated in situ from ninhydrin and l-proline) …
cycloaddition reaction of azomethine ylide (generated in situ from ninhydrin and l-proline) …
Bromine-Promoted One-Pot Furo[b]annulation and α-C(sp2)-Thiomethylation Cascade of (E)-3-Styrylquinoxalin-2(1H)-ones with Dimethyl Sulfoxide
VA Mamedov, NE Algaeva, VV Syakaev… - The Journal of …, 2022 - ACS Publications
A new process has been developed for the bromine-promoted sequential (sp2) C=(sp2) C
bond functionalization of (E)-3-styrylquinoxalin-2 (1 H)-ones and furo [b] annulation via the 5 …
bond functionalization of (E)-3-styrylquinoxalin-2 (1 H)-ones and furo [b] annulation via the 5 …
A General Radical Functionalization of Quinoxalin-2(1H)-ones via a Donor–Acceptor Inversion Strategy
C Niu, J Yang, K Yan, Z Su, B Li… - The Journal of Organic …, 2024 - ACS Publications
The radical donor–acceptor inversion strategy represents a highly promising approach in
the field of radical chemistry. The present study initially describes a metal-free, versatile, and …
the field of radical chemistry. The present study initially describes a metal-free, versatile, and …
I2/TBHP Reagent System: A Modern Paradigm for Organic Transformations**
N Slathia, A Gupta, KK Kapoor - European Journal of Organic …, 2022 - Wiley Online Library
Molecular iodine in combination with TBHP offers an advanced concept for organic
synthesis and catalysis by improving the selectivity and sustainability of organic …
synthesis and catalysis by improving the selectivity and sustainability of organic …
Synthesis of 2-styryl-quinazoline and 3-styryl-quinoxaline based sulfonate esters via sp 3 C–H activation and their evaluation for α-glucosidase inhibition
Synthesis of 2-styryl-quinazolines and 3-styryl-quinoxaline based sulfonates is reported via
sp3 C–H functionalization in the presence of triethylamine (10 mol%). The resulting …
sp3 C–H functionalization in the presence of triethylamine (10 mol%). The resulting …
Comprehensive review on versatile pharmacology of quinoxaline derivative
V Bala Aakash, N Ramalakshmi… - Russian Journal of …, 2022 - Springer
Quinoxaline is a nitrogen-containing heterocyclic compound having many pharmaceutical
and industrial purposes. It can be synthesized by adopting green chemistry principles. The …
and industrial purposes. It can be synthesized by adopting green chemistry principles. The …