Impact of cannabinoids on pregnancy, reproductive health, and offspring outcomes

JO Lo, JC Hedges, G Girardi - American journal of obstetrics and …, 2022 - Elsevier
Cannabis is the most commonly used federally illegal drug in the United States and the
world, especially among people of reproductive age. In addition, the potency of cannabis …

Prenatal cannabinoid exposure: emerging evidence of physiological and neuropsychiatric abnormalities

MG Nashed, DB Hardy, SR Laviolette - Frontiers in psychiatry, 2021 - frontiersin.org
Clinical reports of cannabis use prevalence during pregnancy vary widely from 3% to
upwards of 35% in North America; this disparity likely owing to underestimates from self …

Maternal cannabis use is associated with suppression of immune gene networks in placenta and increased anxiety phenotypes in offspring

G Rompala, Y Nomura, YL Hurd - Proceedings of the …, 2021 - National Acad Sciences
While cannabis is among the most used recreational drugs during pregnancy, the impact of
maternal cannabis use (mCB) on fetal and child development remains unclear. Here, we …

Quality of life and a surveillant endocannabinoid system

RA de Melo Reis, AR Isaac, HR Freitas… - Frontiers in …, 2021 - frontiersin.org
The endocannabinoid system (ECS) is an important brain modulatory network. ECS
regulates brain homeostasis throughout development, from progenitor fate decision to neuro …

Cannabis use in pregnancy and maternal and infant outcomes: A Canadian cross-jurisdictional population-based cohort study

S Luke, AJ Hobbs, M Smith, C Riddell, P Murphy… - PLoS …, 2022 - journals.plos.org
Background With the recent legalization of cannabis in Canada, there is an urgent need to
understand the effect of cannabis use in pregnancy. Our population-based study …

Prenatal THC exposure induces long-term, sex-dependent cognitive dysfunction associated with lipidomic and neuronal pathology in the prefrontal cortex …

MH Sarikahya, SL Cousineau, M De Felice… - Molecular …, 2023 - nature.com
With increasing maternal cannabis use, there is a need to investigate the lasting impact of
prenatal exposure to Δ9-tetrahydrocannabinol (THC), the main psychotropic compound in …

Fetal exposure to cannabis and childhood metabolic outcomes: the Healthy Start Study

BF Moore, KA Sauder, ALB Shapiro… - The Journal of …, 2022 - academic.oup.com
Objective To assess the impact of fetal exposure to cannabis on adiposity and glucose-
insulin traits in early life. Research Design and Methods We leveraged a subsample of 103 …

Cannabis and pregnancy: a review

S Hayer, AD Mandelbaum, L Watch… - Obstetrical & …, 2023 - journals.lww.com
Cannabis and Pregnancy: A Review : Obstetrical & Gynecological Survey Cannabis and
Pregnancy: A Review : Obstetrical & Gynecological Survey Log in or Register Subscribe to …

Chronic prenatal delta-9-tetrahydrocannabinol exposure adversely impacts placental function and development in a rhesus macaque model

VHJ Roberts, MC Schabel, ER Boniface, RJ D'Mello… - Scientific Reports, 2022 - nature.com
Cannabis use in pregnancy is associated with adverse perinatal outcomes, which are likely
mediated by the placenta. However, the underlying mechanisms and specific vasoactive …

Neonatal outcomes associated with in utero cannabis exposure: a population-based retrospective cohort study

LA Avalos, SR Adams, SE Alexeeff… - American Journal of …, 2024 - Elsevier
Background The full spectrum of associations between in utero cannabis exposure and
adverse neonatal outcomes is still unclear. Objective This study aimed to evaluate the …