[HTML][HTML] The safety and anti-ageing effects of nicotinamide mononucleotide in human clinical trials: an update
Q Song, X Zhou, K Xu, S Liu, X Zhu, J Yang - Advances in nutrition, 2023 - Elsevier
The importance of nicotinamide adenine dinucleotide (NAD+) in human physiology is well
recognized. As the NAD+ concentration in human skin, blood, liver, muscle and brain are …
recognized. As the NAD+ concentration in human skin, blood, liver, muscle and brain are …
Self-assembly systems to troubleshoot metabolic engineering challenges
Z Chen, T Wu, S Yu, M Li, X Fan, YX Huo - Trends in Biotechnology, 2024 - cell.com
Enzyme self-assembly is a technology in which enzyme units can aggregate into ordered
macromolecules, assisted by scaffolds. In metabolic engineering, self-assembly strategies …
macromolecules, assisted by scaffolds. In metabolic engineering, self-assembly strategies …
Systematic Engineering of Escherichia coli for Efficient Production of Nicotinamide Mononucleotide From Nicotinamide
Z Huang, N Li, S Yu, W Zhang, T Zhang… - ACS Synthetic …, 2022 - ACS Publications
Research studies on NAD+ have proven its crucial role in aging and disease. Nicotinamide
mononucleotide (NMN), as the key intermediate of NAD+, plays a significant role in …
mononucleotide (NMN), as the key intermediate of NAD+, plays a significant role in …
Directed evolution of phosphite dehydrogenase to cycle noncanonical redox cofactors via universal growth selection platform
Noncanonical redox cofactors are attractive low-cost alternatives to nicotinamide adenine
dinucleotide (phosphate)(NAD (P)+) in biotransformation. However, engineering enzymes to …
dinucleotide (phosphate)(NAD (P)+) in biotransformation. However, engineering enzymes to …
A holistic approach for process intensification of nicotinamide mononucleotide production via high cell density cultivation under exponential feeding strategy
Nicotinamide mononucleotide (NMN) subsists in all living organisms and has drawn
tremendous attention as a nutraceutical and pharmaceutical product for several diseases …
tremendous attention as a nutraceutical and pharmaceutical product for several diseases …
Orthogonal glycolytic pathway enables directed evolution of noncanonical cofactor oxidase
Noncanonical cofactor biomimetics (NCBs) such as nicotinamide mononucleotide (NMN+)
provide enhanced scalability for biomanufacturing. However, engineering enzymes to …
provide enhanced scalability for biomanufacturing. However, engineering enzymes to …
Yeast cell surface engineering of a nicotinamide riboside kinase for the production of β-nicotinamide mononucleotide via whole-cell catalysis
Z He, X Yang, X Tian, L Li, M Liu - ACS Synthetic Biology, 2022 - ACS Publications
β-Nicotinamide mononucleotide (NMN) has been widely used as a nutraceutical for self-
medication. The one-step conversion of nicotinamide riboside (NR) to β-NMN has been …
medication. The one-step conversion of nicotinamide riboside (NR) to β-NMN has been …
Technology and functional insights into the nicotinamide mononucleotide for human health
Y Liu, JS Gong, G Marshall, C Su, JS Shi… - Applied Microbiology and …, 2023 - Springer
Nicotinamide mononucleotide (NMN), a naturally occurring biologically active nucleotide,
mainly functions via mediating the biosynthesis of NAD+. In recent years, its excellent …
mainly functions via mediating the biosynthesis of NAD+. In recent years, its excellent …
[HTML][HTML] Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging
Nicotinamide adenine dinucleotide (NAD+) has recently attracted much attention due to its
role in aging and lifespan extension. NAD+ directly and indirectly affects many cellular …
role in aging and lifespan extension. NAD+ directly and indirectly affects many cellular …
Biosynthesis of nicotinamide mononucleotide: Current metabolic engineering strategies, challenges, and prospects
S Luo, J Zhao, Y Zheng, T Chen, Z Wang - Fermentation, 2023 - mdpi.com
Nicotinamide mononucleotide (NMN) is an essential precursor of nicotinamide adenine
dinucleotide (NAD+), which is widely applied in the pharmaceutical and biotech industries …
dinucleotide (NAD+), which is widely applied in the pharmaceutical and biotech industries …