According to numerous animal studies, adverse environmental stimuli, including physical,
chemical, and biological factors, can cause low‐grade chronic inflammation and subsequent …

Mitochondria are fascinating structures of the cellular compartments that generate energy to
run the cells. However, inherent disorders of mitochondria due to diabetes can cause major …

Most mortality and morbidity following exposure to vesicants such as sulfur mustard is due to
pulmonary toxicity. Acute injury is characterized by epithelial detachment and necrosis in the …

Background: The phenotypic expression of sickle cell disease (SCD) is a complex
pathophysiologic condition. However, sickle erythrocytes might be the cause for multiple …

Aloesone is a major metabolic compound in Aloe vera, which has been widely used as a
food source and therapeutic agent in several countries. Our recent study demonstrated that …

Growing evidences suggest that excess generation of highly reactive free oxygen/nitrogen
radicals (ROS/RNS) are largely due to hyperglycemia causes oxidative stress. Further …

High glucose-induced increase in production of reactive oxygen/nitrogen species
(ROS/RNS) is recognized as a major cause of the clinical complications associated with …

Growing evidence indicates that skin injuries are a common complication of diabetes.
However, the cellular and molecular mechanisms of high glucose (HG) environment trigger …

Lipopolysaccharide disturbs the secretion of gonadotropin, endometrial function and
implantation efficiency. However, there is little information regarding the effects of …

Reactive oxygen species (ROS) is mainly produced as a by-product from electron transport
chain (ETC) of mitochondria and effectively eliminated by cellular antioxidants. However, 2 …