Osteoporosis represents an important cause of morbidity in adult patients with thalassaemia
major (TM). The pathogenesis of osteoporosis in TM is multifactorial, and includes bone …

Increased survival in patients with β thalassemia major (TM) allowed for several
complications of the disease and its treatment to manifest, one of which is bone disease …

Background The combination of transfusion and chelation therapy has dramatically
extended the life expectancy of thalassemic patients. The main objective of this study is to …

Anemia in childhood is defined as a hemoglobin (Hb) concentration below cut off levels
established by the World Health Organization:< 11 g/dl in children aged 6–59 months,< 11.5 …

Thalassemia/hemoglobinopathy is a hereditary disease that causes chronic anemia and
increased erythropoiesis. Consequently, an expansion of bone marrow spaces may …

Bone disease is an important cause of morbidity in older patients with β‐thalassaemia major
and intermedia. We studied 27 women and 23 men with β‐thalassaemia major (37) and …

Bone mass acquired during childhood and adolescence is a key determinant of adult bone
health. Peak bone mass, which is achieved in late adolescence, is a main determinant of …

Fragility fracture is a worldwide problem and a main cause of disability and impaired quality
of life. It is primarily caused by osteoporosis, characterized by impaired bone quantity and or …

Secondary osteoporosis is a common clinical problem faced by bone specialists, with a
higher frequency in men than in women. One of several causes of secondary osteoporosis is …

Bone disease in patients with thalassaemia major is a multifactorial and still poorly
understood process. The present study evaluated 45 thalassaemic patients using dual X‐ray …