Cysteine aminotransferase (CAT): a pivotal sponsor in metabolic remodeling and an ally of 3-mercaptopyruvate sulfurtransferase (MST) in cancer

A Hipólito, SC Nunes, JB Vicente, J Serpa - Molecules, 2020 - mdpi.com
Metabolic remodeling is a critical skill of malignant cells, allowing their survival and spread.
The metabolic dynamics and adaptation capacity of cancer cells allow them to escape from …

Genetic architecture of gene expression in European and African Americans: an eQTL mapping study in GENOA

L Shang, JA Smith, W Zhao, M Kho, ST Turner… - The American Journal of …, 2020 - cell.com
Most existing expression quantitative trait locus (eQTL) mapping studies have been focused
on individuals of European ancestry and are underrepresented in other populations …

Persistent elevation of aspartate aminotransferase in a child after incomplete Kawasaki disease: a case report and literature review

P Rohani, F Imanzadeh, A Sayyari, M Kazemi Aghdam… - BMC pediatrics, 2020 - Springer
Background Interpretation of abnormalities in liver function tests, especially in asymptomatic
children, is a common problem faced by clinicians. Isolated elevation of aspartate …

Whole‐exome sequencing identifies novel pathogenic variants across the ATP7B gene and some modifiers of Wilson's disease phenotype

A Kluska, M Kulecka, T Litwin, K Dziezyc… - Liver …, 2019 - Wiley Online Library
Abstract Background & Aims Wilson's disease (WD) is an autosomal recessive disorder
associated with disease‐causing alterations across the ATP7B gene, with highly variable …

Analysis of the uterine lumen in fertility-classified heifers: II. Proteins and metabolites

JGN Moraes, SK Behura, JV Bishop… - Biology of …, 2020 - academic.oup.com
Survival and growth of the bovine conceptus is dependent on endometrial secretions or
histotroph. Previously, serial blastocyst transfer was used to classify heifers as high fertile …

Saline-alkali stress tolerance is enhanced by MhPR1 in Malus halliana leaves as shown by transcriptomic analyses

R Zhang, Z Zhang, S Wang, T Zhao, D Zhang, N Ma… - Planta, 2022 - Springer
Main conclusion qRT-PCR analysis showed that MhPR1 was strongly induced by saline-
alkali stress. Overexpression of MhPR1 enhanced tolerance to saline-alkali stress in …

Proteomic analysis of the hepatotoxicity of Microcystis aeruginosa in adult zebrafish (Danio rerio) and its potential mechanisms

B Du, G Liu, M Ke, Z Zhang, M Zheng, T Lu, L Sun… - Environmental …, 2019 - Elsevier
Microcystis aeruginosa is one of the main species of cyanobacteria that causes water
blooms. M. aeruginosa can release into the water several types of microcystins (MCs), which …

Identification of serum biomarkers to distinguish hazardous and benign aminotransferase elevations

JH Vazquez, MM Clemens, FD Allard… - Toxicological …, 2020 - academic.oup.com
The standard circulating biomarker of liver injury in both clinical settings and drug safety
testing is alanine aminotransferase (ALT). However, ALT elevations sometimes lack …

Association between aspartate aminotransferase to alanine aminotransferase ratio and mortality in critically ill patients with congestive heart failure

Y Bian, H Kou, Z Jia, Q Cui, P Wu, J Ma, X Ma, P Jin - Scientific Reports, 2024 - nature.com
Congestive heart failure (CHF) is a complex clinical syndrome that significantly impacts
patient outcomes, especially in critically ill patients admitted to intensive care units (ICUs) …

The significance of isolated aspartate aminotransferase elevation in healthy paediatric patients

R Magen‐Rimon, G Tal, M Kaplan, R Shaoul - Acta Paediatrica, 2022 - Wiley Online Library
Aim Aspartate aminotransferase (AST) is an enzyme expressed in several organs; therefore,
AST elevation may reflect outside of liver pathology. AST elevation may also be associated …