Comprehensive review of medicinal marijuana, cannabinoids, and therapeutic implications in medicine and headache: what a long strange trip it's been…

EP Baron - Headache: The Journal of Head and Face Pain, 2015 - Wiley Online Library
Background The use of cannabis, or marijuana, for medicinal purposes is deeply rooted
though history, dating back to ancient times. It once held a prominent position in the history …

Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities

RG Pertwee - … Transactions of the Royal Society B …, 2012 - royalsocietypublishing.org
Human tissues express cannabinoid CB1 and CB2 receptors that can be activated by
endogenously released 'endocannabinoids' or exogenously administered compounds in a …

[HTML][HTML] The use of cannabinoids in the treatment of inflammatory bowel disease (IBD): a review of the literature

BN Nduma, KA Mofor, J Tatang, C Ekhator, S Ambe… - Cureus, 2023 - ncbi.nlm.nih.gov
Around the world, about 15 to 40% of individuals with inflammatory bowel disease (IBD) rely
on cannabis and cannabinoids to reduce the need for other medications, as well as increase …

Polypharmacological properties and therapeutic potential of β-caryophyllene: a dietary phytocannabinoid of pharmaceutical promise

C Sharma, JM Al Kaabi, SM Nurulain… - Current …, 2016 - ingentaconnect.com
Background: β-Caryophyllene (BCP) is a natural bicyclic sesquiterpene abundantly found in
essential oils from various spices, fruits and medicinal as well as ornamental plants. It is …

[HTML][HTML] Endocannabinoid system as a promising therapeutic target in inflammatory bowel disease–a systematic review

S Hryhorowicz, M Kaczmarek-Ryś, A Zielińska… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) is a general term used to describe a group of chronic
inflammatory conditions of the gastrointestinal tract of unknown etiology, including two …

Cannabinoids and autoimmune diseases: A systematic review

V Katchan, P David, Y Shoenfeld - Autoimmunity reviews, 2016 - Elsevier
Cannabinoids have shown to have a variety effects on body systems. Through CB1 and CB2
receptors, amongst other, they exert an effect by modulating neurotransmitter and cytokine …

Complementary and alternative medicines used by patients with inflammatory bowel diseases

AS Cheifetz, R Gianotti, R Luber, PR Gibson - Gastroenterology, 2017 - Elsevier
Patients and physicians often have many questions regarding the role of complementary
and alternative medicines (CAMs), or nonallopathic therapies, for inflammatory bowel …

[HTML][HTML] Targeting NLRP3 inflammasome in inflammatory bowel disease: putting out the fire of inflammation

BZ Shao, SL Wang, P Pan, J Yao, K Wu, ZS Li, Y Bai… - Inflammation, 2019 - Springer
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and
small intestine, comprised of ulcerative colitis and Crohn's disease. Among the complicated …

The K2/Spice phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products

LK Brents, PL Prather - Drug metabolism reviews, 2014 - Taylor & Francis
Abstract In 2008, the European Monitoring Center for Drugs and Drug Addiction (EMCDDA)
detected unregulated, psychoactive synthetic cannabinoids (SCBs) in purportedly all-natural …

[HTML][HTML] Effects of cannabinoids on T-cell function and resistance to infection

TK Eisenstein, JJ Meissler - Journal of Neuroimmune Pharmacology, 2015 - Springer
This review examines the effects of cannabinoids on immune function, with a focus on
effects on T-cells, as well as on resistance to infection. The paper considers the immune …