Potential genetic and epigenetic mechanisms in insomnia: A systematic review
L Palagini, PA Geoffroy, PR Gehrman… - Journal of Sleep …, 2023 - Wiley Online Library
Insomnia is a stress‐related sleep disorder conceptualised within a diathesis‐stress
framework, which it is thought to result from predisposing factors interacting with …
framework, which it is thought to result from predisposing factors interacting with …
Integrating genetics and transcriptomics to study major depressive disorder: a conceptual framework, bioinformatic approaches, and recent findings
Major depressive disorder (MDD) is a complex and heterogeneous psychiatric syndrome
with genetic and environmental influences. In addition to neuroanatomical and circuit-level …
with genetic and environmental influences. In addition to neuroanatomical and circuit-level …
Shared genetics and causality between decaffeinated coffee consumption and neuropsychiatric diseases: a large-scale genome-wide cross-trait analysis and …
Coffee or caffeine consumption has been associated with neuropsychiatric disorders,
implying a shared etiology. However, whether these associations reflect causality remains …
implying a shared etiology. However, whether these associations reflect causality remains …
The function and structure of Precuneus is associated with subjective sleep quality in major depression
L Ma, C Zhang - Frontiers in Psychiatry, 2022 - frontiersin.org
Background Poor sleep quality is related to depression. However, the investigation of the
neural basis for poor sleep quality in individuals with major depression (MD) is limited …
neural basis for poor sleep quality in individuals with major depression (MD) is limited …
Shared genetic mechanisms underlying association between sleep disturbances and depressive symptoms
M Moyses-Oliveira, M Zamariolli, PF Tempaku… - Sleep Medicine, 2024 - Elsevier
Objectives Polygenic scores (PGS) for sleep disturbances and depressive symptoms in an
epidemiological cohort were contrasted. The overlap between genes assigned to variants …
epidemiological cohort were contrasted. The overlap between genes assigned to variants …
[HTML][HTML] 从突触可塑性出发探讨抑郁症和失眠的共病双向机制
孟繁昊， 王珑 - Journal of Central South University Medical …, 2023 - ncbi.nlm.nih.gov
失眠是抑郁症最常见的伴随症状之一， 二者具有高度重合的分子机制。 通过相似的病理学改变
可以引发失眠和抑郁症的共病， 随着病程进展可能形成恶性循环。 因此， 了解失眠 …
可以引发失眠和抑郁症的共病， 随着病程进展可能形成恶性循环。 因此， 了解失眠 …
Integrative Functional Genomic Analysis in Multiplex Autism Families from Kazakhstan
A Perfilyeva, K Bespalova, Y Perfilyeva… - Disease …, 2022 - Wiley Online Library
The study of extended pedigrees containing autism spectrum disorder‐(ASD‐) related
broader autism phenotypes (BAP) offers a promising approach to the search for ASD …
broader autism phenotypes (BAP) offers a promising approach to the search for ASD …
Large-scale composite hypothesis testing for omics analyses
A De Walsche, F Gauthier, A Charcosset, T Mary-Huard - bioRxiv, 2024 - biorxiv.org
Abstract Composite Hypothesis Testing (CHT) based on summary statistics has become a
popular strategy to assess the effect of a same marker (or gene) jointly across multiple traits …
popular strategy to assess the effect of a same marker (or gene) jointly across multiple traits …
Bidirectional mechanism of comorbidity of depression and insomnia based on synaptic plasticity.
F Meng, L Wang - Zhong nan da xue xue bao. Yi xue ban= Journal …, 2023 - europepmc.org
失眠是抑郁症最常见的伴随症状之一, 二者具有高度重合的分子机制. 通过相似的病理学改变
可以引发失眠和抑郁症的共病, 随着病程进展可能形成恶性循环. 因此, 了解失眠 …
可以引发失眠和抑郁症的共病, 随着病程进展可能形成恶性循环. 因此, 了解失眠 …