Pseudomonas aeruginosa Biofilms

MTT Thi, D Wibowo, BHA Rehm - International journal of molecular …, 2020 - mdpi.com
Pseudomonas aeruginosa is an opportunistic human pathogen causing devastating acute
and chronic infections in individuals with compromised immune systems. Its highly notorious …

Global threat of carbapenem-resistant gram-negative bacteria

SS Jean, D Harnod, PR Hsueh - Frontiers in cellular and infection …, 2022 - frontiersin.org
Infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-
negative bacteria (GNB), including carbapenem-resistant (CR) Enterobacterales (CRE; …

[HTML][HTML] Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

Z Pang, R Raudonis, BR Glick, TJ Lin, Z Cheng - Biotechnology advances, 2019 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …

Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler

B Van Nieuwenhuyse, D Van der Linden… - Nature …, 2022 - nature.com
Post-operative bacterial infections are a leading cause of mortality and morbidity after
ongoing liver transplantation. Bacteria causing these infections in the hospital setting can …

Bacteriophage therapy against Pseudomonas aeruginosa biofilms: a review

Z Chegini, A Khoshbayan, M Taati Moghadam… - Annals of clinical …, 2020 - Springer
Abstract Multi-Drug Resistant (MDR) Pseudomonas aeruginosa is one of the most important
bacterial pathogens that causes infection with a high mortality rate due to resistance to …

[HTML][HTML] Biofilms: Formation, drug resistance and alternatives to conventional approaches

R Mirghani, T Saba, H Khaliq, J Mitchell, L Do… - AIMS …, 2022 - ncbi.nlm.nih.gov
Biofilms are aggregates of bacteria, in most cases, which are resistant usually to broad-
spectrum antibiotics in their typical concentrations or even in higher doses. A trend of …

Recombinant endolysins as potential therapeutics against antibiotic-resistant Staphylococcus aureus: current status of research and novel delivery strategies

H Haddad Kashani, M Schmelcher… - Clinical microbiology …, 2018 - Am Soc Microbiol
Staphylococcus aureus is one of the most common pathogens of humans and animals,
where it frequently colonizes skin and mucosal membranes. It is of major clinical importance …

In vitro techniques and measurements of phage characteristics that are important for phage therapy success

T Glonti, JP Pirnay - Viruses, 2022 - mdpi.com
Validated methods for phage selection, host range expansion, and lytic activity
determination are indispensable for maximizing phage therapy outcomes. In this review, we …

How phages overcome the challenges of drug resistant bacteria in clinical infections

M Taati Moghadam, N Amirmozafari… - Infection and Drug …, 2020 - Taylor & Francis
Nowadays the most important problem in the treatment of bacterial infections is the
appearance of MDR (multidrug-resistant), XDR (extensively drug-resistant) and PDR (pan …

Mechanisms and Targeted Therapies for Pseudomonas aeruginosa Lung Infection

CS Curran, T Bolig, P Torabi-Parizi - American journal of respiratory …, 2018 - atsjournals.org
Pseudomonas aeruginosa is a complex gram-negative facultative anaerobe replete with a
variety of arsenals to activate, modify, and destroy host defense mechanisms. The microbe is …