Update in Duchenne and Becker muscular dystrophy

MA Waldrop, KM Flanigan - Current opinion in neurology, 2019 - journals.lww.com
The mainstay of treatment remains meeting well defined standards of care that have been
shown to influence morbidity and mortality. These include use of systemic steroids, early …

A current approach to heart failure in Duchenne muscular dystrophy

D D'Amario, A Amodeo, R Adorisio, FD Tiziano… - Heart, 2017 - heart.bmj.com
Duchenne muscular dystrophy (DMD) is a genetic, progressive neuromuscular condition
that is marked by the long-term muscle deterioration with significant implications of …

Cardiac management of the patient with Duchenne muscular dystrophy

S Buddhe, L Cripe, J Friedland-Little, N Kertesz… - …, 2018 - publications.aap.org
Duchenne muscular dystrophy (DMD) results in a progressive cardiomyopathy that
produces significant morbidity and mortality. To improve the quality of life in patients with …

Cardiorespiratory management of Duchenne muscular dystrophy: emerging therapies, neuromuscular genetics, and new clinical challenges

DJ Birnkrant, L Bello, RJ Butterfield… - The Lancet …, 2022 - thelancet.com
The life-limiting complications of Duchenne muscular dystrophy (DMD) include loss of lung
function and progressive cardiomyopathy; when patients are treated with assisted …

Duchenne dilated cardiomyopathy: cardiac management from prevention to advanced cardiovascular therapies

R Adorisio, E Mencarelli, N Cantarutti… - Journal of clinical …, 2020 - mdpi.com
Duchenne muscular dystrophy (DMD) cardiomyopathy (DCM) is characterized by a
hypokinetic, dilated phenotype progressively increasing with age. Regular cardiac care is …

Clinical management of Duchenne muscular dystrophy: the state of the art

S Messina, GL Vita - Neurological Sciences, 2018 - Springer
Introduction Duchenne muscular dystrophy (DMD) is a devastating, progressive
neuromuscular disorder for which there is no cure. As the dystrophin gene is located on the …

ISHLT consensus statement for the selection and management of pediatric and congenital heart disease patients on ventricular assist devices Endorsed by the …

A Lorts, J Conway, M Schweiger, I Adachi… - The Journal of Heart …, 2021 - jhltonline.org
Background Heart failure (HF) is a significant cause of mortality in children and therefore
there is interest in understanding the optimal way to support these children with Ventricular …

[HTML][HTML] Essential roles of the dystrophin-glycoprotein complex in different cardiac pathologies

IC Valera, AL Wacker, HS Hwang, C Holmes… - Advances in medical …, 2021 - Elsevier
The dystrophin-glycoprotein complex (DGC), situated at the sarcolemma dynamically
remodels during cardiac disease. This review examines DGC remodeling as a common …

Dystrophin cardiomyopathies: clinical management, molecular pathogenesis and evolution towards precision medicine

D D'Amario, A Gowran, F Canonico… - Journal of clinical …, 2018 - mdpi.com
Duchenne's muscular dystrophy is an X-linked neuromuscular disease that manifests as
muscle atrophy and cardiomyopathy in young boys. However, a considerable percentage of …

Duchenne muscular dystrophy: the heart of the matter

JA Shih, A Folch, BL Wong - Current heart failure reports, 2020 - Springer
Abstract Purpose of Review Duchenne muscular dystrophy is one of many neuromuscular
disorders, but it frequently causes severe disability early in life and early death. Cardiac …