Elicitation, an effective strategy for the biotechnological production of bioactive high-added value compounds in plant cell factories

K Ramirez-Estrada, H Vidal-Limon, D Hidalgo… - Molecules, 2016 - mdpi.com
Plant in vitro cultures represent an attractive and cost-effective alternative to classical
approaches to plant secondary metabolite (PSM) production (the “Plant Cell Factory” …

Unravelling the multi-faceted regulatory role of polyamines in plant biotechnology, transgenics and secondary metabolomics

S Nandy, T Das, CK Tudu, T Mishra, M Ghorai… - Applied Microbiology …, 2022 - Springer
Polyamines (PAs) are ubiquitous low-molecular-weight, aliphatic compounds with wide as
well as complex application in fundamental areas of plant growth and development. PAs are …

Metabolic engineering tanshinone biosynthetic pathway in Salvia miltiorrhiza hairy root cultures

G Kai, H Xu, C Zhou, P Liao, J Xiao, X Luo, L You… - Metabolic …, 2011 - Elsevier
Tanshinone is a group of active diterpenes widely used in treatment of cardiovascular
diseases. Here, we report the introduction of genes encoding 3-hydroxy-3-methylglutaryl …

Effects of methyl jasmonate and salicylic acid on tanshinone production and biosynthetic gene expression in transgenic Salvia miltiorrhiza hairy roots

X Hao, M Shi, L Cui, C Xu, Y Zhang… - Biotechnology and …, 2015 - Wiley Online Library
Tanshinone is a group of active diterpenes, which are widely used in the treatment of
cardiovascular disease. In this study, methyl jasmonate (MJ) and salicylic acid (SA) were …

Production and metabolic engineering of bioactive substances in plant hairy root culture

ML Zhou, XM Zhu, JR Shao, YX Tang… - Applied microbiology and …, 2011 - Springer
In the past three decades, hairy roots research for the production of valuable biological
active substances has received a lot of attention. The addition of knowledge to enhance the …

Effective elicitors and process strategies for enhancement of secondary metabolite production in hairy root cultures

JW Wang, JY Wu - Biotechnology of hairy root systems, 2013 - Springer
<? xm-replace_text {Heading}?> Abstract This chapter reviews the various biotic and abiotic
elicitors applied to hairy root cultures and their stimulating effects on the accumulation of …

Occurrence of tropane alkaloids in food

PPJ Mulder, M de Nijs, M Castellari… - EFSA Supporting …, 2016 - Wiley Online Library
A total of 1709 samples of plant-derived food products, mainly produced in Europe, were
analysed for tropane alkaloids (TAs). The samples, of which 27.4% came from organic …

Enhanced flavonoid production in hairy root cultures of Glycyrrhiza uralensis Fisch by combining the over-expression of chalcone isomerase gene with the elicitation …

HC Zhang, JM Liu, HY Lu, SL Gao - Plant Cell Reports, 2009 - Springer
Economically important compounds, such as licorice flavonoids, are present in insufficient
amounts in the hairy roots. To overcome this problem, we took the transgenic approach …

Polyamine interactions with plant hormones: crosstalk at several levels

R Anwar, AK Mattoo, AK Handa - … : a universal molecular nexus for growth …, 2015 - Springer
Polyamines play important roles in diverse plant growth and development processes,
including seed germination, tissue lignification, organogenesis, flowering, pollination …

Improved tropane alkaloid production and changes in gene expression in hairy root cultures of two Hyoscyamus species elicited by silicon dioxide nanoparticles

A Hedayati, B Hosseini, J Palazon, R Maleki - Plant Physiology and …, 2020 - Elsevier
Species of Hyoscyamus are rich sources of medicinally important tropane alkaloids, which
have anticholinergic, antispasmodic and sedative effects and are competitive inhibitors of …