Regulation of skeletal myogenesis by microRNAs

M Xu, X Chen, D Chen, B Yu, M Li… - Journal of cellular …, 2020 - Wiley Online Library
Skeletal muscle development is a highly organized process controlled by evolutionarily
conserved networks of transcription factors, transferrable signaling molecules, and …

Tiny regulators of massive tissue: MicroRNAs in skeletal muscle development, myopathies, and cancer cachexia

GB Singh, DB Cowan, DZ Wang - Frontiers in oncology, 2020 - frontiersin.org
Skeletal muscles are the largest tissues in our body and the physiological function of muscle
is essential to every aspect of life. The regulation of development, homeostasis, and …

A comprehensive epigenome atlas reveals DNA methylation regulating skeletal muscle development

Y Yang, X Fan, J Yan, M Chen, M Zhu… - Nucleic acids …, 2021 - academic.oup.com
DNA methylation is important for the epigenetic regulation of gene expression and plays a
critical role in mammalian development. However, the dynamic regulation of genome-wide …

circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop

J Yan, Y Yang, X Fan, G Liang, Z Wang… - Journal of cachexia …, 2022 - Wiley Online Library
Abstract Background Circular RNAs (circRNAs) represent a novel class of non‐coding RNAs
formed by a covalently closed loop and play crucial roles in many biological processes …

The genome variation and developmental transcriptome maps reveal genetic differentiation of skeletal muscle in pigs

Y Yang, J Yan, X Fan, J Chen, Z Wang, X Liu, G Yi… - PLoS …, 2021 - journals.plos.org
Natural and artificial directional selections have resulted in significantly genetic and
phenotypic differences across breeds in domestic animals. However, the molecular …

Differentiation of mesenchymal stem cells into cardiomyocytes is regulated by miRNA-1-2 via WNT signaling pathway

X Shen, B Pan, H Zhou, L Liu, T Lv, J Zhu… - Journal of biomedical …, 2017 - Springer
Background Bone marrow derived stem cells (BMSCs) have the potential to differentiate into
cardiomyocytes, but the rate of differentiation is low and the mechanism of differentiation is …

miR-378a-3p promotes differentiation and inhibits proliferation of myoblasts by targeting HDAC4 in skeletal muscle development

X Wei, H Li, B Zhang, C Li, D Dong, X Lan, Y Huang… - RNA biology, 2016 - Taylor & Francis
Muscle development, or myogenesis, is a highly regulated, complex process. A subset of
microRNAs (miRNAs) have been identified as critical regulators of myogenesis. Recently …

Integrated analysis of miRNA and mRNA paired expression profiling of prenatal skeletal muscle development in three genotype pigs

Z Tang, Y Yang, Z Wang, S Zhao, Y Mu, K Li - Scientific reports, 2015 - nature.com
MicroRNAs (miRNAs) play a vital role in muscle development by binding to messenger
RNAs (mRNAs). Based on prenatal skeletal muscle at 33, 65 and 90 days post-coitus (dpc) …

Stem cells-derived in vitro meat: from petri dish to dinner plate

A Singh, V Verma, M Kumar, A Kumar… - Critical reviews in …, 2022 - Taylor & Francis
Sustainable food supply to the world is possibly the greatest challenge that human
civilization has ever faced. Among animal sourced foods, meat plays a starring role in …

The NF-κB-modulated microRNAs miR-195 and miR-497 inhibit myoblast proliferation by targeting Igf1r, Insr and cyclin genes

W Wei, WY Zhang, JB Bai, HX Zhang… - Journal of cell …, 2016 - journals.biologists.com
MicroRNAs (miRNAs) play important roles in the development of skeletal muscle. In our
previous study, expression of miR-195 and miR-497 were shown to be upregulated during …