Biological processes are often dynamic, thus researchers must monitor their activity at
multiple time points. The most abundant source of information regarding such dynamic …

Abstract Analysis of gene expression has contributed to a plethora of biological and medical
research studies. Microarrays have been intensively used for the profiling of gene …

When clustering gene expression, it is expected that correlation coefficients of genes in the
same clusters are high, and that gene ontology (GO) enrichment analysis of most clusters …

Gene expression time-course experiments allow to study the dynamics of transcriptomic
changes in cells exposed to different stimuli. However, most approaches for the …

Background Life science research is moving quickly towards large-scale experimental
designs that are comprised of multiple tissues, time points, and samples. Omic time-series …

Measuring expression levels of genes at the whole genome level can be useful for many
purposes, especially for revealing biological pathways underlying specific phenotype …

Purpose This article will briefly review the origins and evolution of functional genomics, first
describing the experimental technology, and then some of the approaches applied to data …

The longitudinal characterisation of Huntington's disease (HD) mouse lines is essential for
the understanding of the differential developmental time course, nature and severity of …

Proteomics is an expanding area of research into biological systems with significance for
biomedical and therapeutic applications ranging from understanding the molecular basis of …

Bisphenol A (BPA) can induce complex regulatory mechanisms in many aquatic organisms,
and it is difficult to find a suitable analytical method to efficiently enrich key genes …