Viral infections have been proven a severe threat to human beings, and the pandemic of
Coronavirus Disease 2019 (COVID-19) has become a societal health concern, including …

Introduction Microneedles are emerging as a promising technology for vaccine delivery, with
numerous advantages over traditional needle and syringe methods. Preclinical studies have …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than
160 million people and resulted in more than 3.3 million deaths, and despite the availability …

In 2022, a genotype IV (GIV) strain of Japanese encephalitis virus (JEV) caused an
unprecedented and widespread outbreak of disease in pigs and humans in Australia. As no …

We recently developed a chimeric flavivirus vaccine technology based on the novel insect-
specific Binjari virus (BinJV) and used this to generate a chimeric ZIKV vaccine (BinJ/ZIKA …

West Nile virus (WNV) causes skin lesions in farmed crocodiles leading to the depreciation
of the value of their hides and significant economic losses. However, there is no …

Vector-borne flaviviruses are responsible for nearly half a billion human infections
worldwide each year, resulting in millions of cases of debilitating and severe diseases and …

The ongoing SARS-CoV-2 pandemic continues to pose an enormous health challenge
globally. The ongoing emergence of variants of concern has resulted in decreased vaccine …

Zika virus (ZIKV) infections are spreading silently with limited global surveillance in at least
89 countries and territories. There is a pressing need to develop an effective vaccine …

Binjari virus (BinJV) is a lineage II or dual-host affiliated insect-specific flavivirus previously
demonstrated as replication-deficient in vertebrate cells. Previous studies have shown that …