Novel quinoline-based thiosemicarbazide derivatives: synthesis, DFT calculations, and investigation of antitubercular, antibacterial, and antifungal activities

E Özcan, SK Vagolu, MG Gündüz… - ACS …, 2023 - ACS Publications
The discovery of new antimicrobial agents as a means of treating drug-resistant microbial
pathogens is of utmost significance to overcome their immense risk to human well-being …

Linking quinoline ring to 5-nitrofuran moiety via sulfonyl hydrazone bridge: Synthesis, structural characterization, DFT studies, and evaluation of antibacterial and …

ŞD Doğan, E Özcan, Y Çetinkaya, Mİ Han… - Journal of Molecular …, 2023 - Elsevier
In the present work, we report the synthesis, structural characterization, and computational
studies of (E)-N'-((5-nitrofuran-2-yl) methylene) quinoline-8-sulfonohydrazide (QNF) as a …

AlCl3-Catalyzed Cascade Reactions of 1,2,3-Trimethoxybenzene and Adipoyl Chloride: Spectroscopic Investigations and Density Functional Theory Studies

Y Çetinkaya, T Artunç, A Menzek - ACS omega, 2022 - ACS Publications
The reaction of 1, 2, 3-trimethoxybenzene with adipoyl chloride in the presence of AlCl3
gave two isomeric cyclopentene derivatives, 1, 6-bis (2, 3, 4-trimethoxyphenyl) hexane-1, 6 …

Synthesis of β-lactams and transformation to β-amino acid ethyl ester derivatives: Theoretical calculations

Y Akbaba, Y Çetinkaya, S Başçeken, A Akıncıoğlu… - Tetrahedron, 2024 - Elsevier
Because of the important biological properties of β-amino acids in the present work, two new
β-amino acid ethyl ester derivatives were synthesized, and their mechanistic occurrence …

Investigation of cholinesterase and α-glucosidase enzyme activities, and molecular docking and dft studies for 1, 2-disubstituted cyclopentane derivatives with phenyl …

T Artunç, Y Çetinkaya, P Taslimi, A Menzek - Molecular Diversity, 2024 - Springer
Abstract Six known products (4–9) were prepared from reaction of adipoyl chloride with 1, 2,
3-trimethoxybenzene according to the literature. From (2, 3, 4-trimethoxyphenyl)(2-(2, 3, 4 …

Synthesis and photooxygenation of 3-(p-substituted phenyl)-3a, 8a-dihydro-4H-cyclohepta [d] isoxazoles: Facial selectivity

ME Olgun, A Menzek, E Şahin… - Turkish Journal of …, 2024 - journals.tubitak.gov.tr
Abstract Two 3-(p-substituted phenyl)-3a, 8a-dihydro-4H-cyclohepta [d] isoxazoles were
synthesized by 1, 3-dipolar cycloaddition of the corresponding nitrile oxides with …