Background Chemotherapy is a first-line treatment for advanced and metastatic bladder
cancer, but the unsatisfactory objective response rate to this treatment yields poor 5-year …

Hematological malignancies are a class of malignant neoplasms attributed to abnormal
differentiation of hematopoietic stem cells (HSCs). The systemic involvement, poor …

Genomic and transcriptomic profiling has enhanced the diagnostic and treatment options for
many cancers. However, the molecular characteristics of parathyroid cancer remain largely …

Background: Ovarian cancer (OC) is the most lethal malignancy in the female reproductive
system. Growing evidences demonstrates that competing endogenous RNA (ceRNA) …

Although primary cilia abnormalities have been frequently observed in multiple cancers,
including prostate cancer (PCa), the molecular mechanisms underlying primary ciliogenesis …

Abnormal expression or mutation of RNA splicing proteins are widely observed in human
cancers. Here, we identified poly (U) binding splicing factor 60 (PUF60) as one of the most …

Background Exosomes have been regarded as emerging tools for cancer diagnosis. Tumor-
derived exosomes contain molecules that enhance cancer progression and affect immune …

As a complex systemic disease, primary liver cancer ranks third in death rate for solid tumors
worldwide. Family with sequence similarity 111 member B (FAM111B), which was found to …

Gene fusions are thought to be driver mutations in multiple cancers and are an important
factor for poor patient prognosis. Most of them appear in specific cancers, thus satisfactory …

Human genital Chlamydia infection is a major public health concern due to the serious
reproductive system complications. Chlamydia binds several receptor tyrosine kinases …