Cannabinoids and the expanded endocannabinoid system in neurological disorders
L Cristino, T Bisogno, V Di Marzo - Nature Reviews Neurology, 2020 - nature.com
Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …
[HTML][HTML] Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities
Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
Microglia in the TBI brain: the good, the bad, and the dysregulated
As the major cellular component of the innate immune system in the central nervous system
(CNS) and the first line of defense whenever injury or disease occurs, microglia play a …
(CNS) and the first line of defense whenever injury or disease occurs, microglia play a …
Alternatively activated microglia and macrophages in the central nervous system
R Franco, D Fernández-Suárez - Progress in neurobiology, 2015 - Elsevier
Macrophages are important players in the fight against viral, bacterial, fungal and parasitic
infections. From a resting state they may undertake two activation pathways, the classical …
infections. From a resting state they may undertake two activation pathways, the classical …
Integrating endocannabinoid signaling and cannabinoids into the biology and treatment of posttraumatic stress disorder
Exposure to stress is an undeniable, but in most cases surmountable, part of life. However,
in certain individuals, exposure to severe or cumulative stressors can lead to an array of …
in certain individuals, exposure to severe or cumulative stressors can lead to an array of …
Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease
JJ Liu, P Green, JJ Mann, SI Rapoport, ME Sublette - Brain research, 2015 - Elsevier
Essential polyunsaturated fatty acids (PUFAs) have profound effects on brain development
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …
Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoyl-glycerol and arachidonoyl-ethanolamide, and their metabolites
C Turcotte, F Chouinard, JS Lefebvre… - Journal of Leucocyte …, 2015 - academic.oup.com
Arachidonoyl-glycerol (2-AG) and arachidonyl-ethanolamide (AEA) are endocannabinoids
that have been implicated in many physiologic disorders, including obesity, metabolic …
that have been implicated in many physiologic disorders, including obesity, metabolic …
Endocannabinoid modulation of microglial phenotypes in neuropathology
M Tanaka, S Sackett, Y Zhang - Frontiers in Neurology, 2020 - frontiersin.org
Microglia, the resident immune cells of the central nervous system, mediate brain
homeostasis by controlling neuronal proliferation/differentiation and synaptic activity. In …
homeostasis by controlling neuronal proliferation/differentiation and synaptic activity. In …
Intracellular molecular targets and signaling pathways involved in antioxidative and neuroprotective effects of cannabinoids in neurodegenerative conditions
In the last few decades, endocannabinoids, plant-derived cannabinoids and synthetic
cannabinoids have received growing interest as treatment options in neurodegenerative …
cannabinoids have received growing interest as treatment options in neurodegenerative …
Measuring anxiety-like behaviors in rodent models of traumatic brain injury
Anxiety is a common complaint following acquired traumatic brain injury (TBI). However, the
measurement of dysfunctional anxiety behavioral states following experimental TBI in …
measurement of dysfunctional anxiety behavioral states following experimental TBI in …