Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …
Airway epithelial barrier dysfunction in chronic obstructive pulmonary disease: role of cigarette smoke exposure
The epithelial lining of the airway forms the first barrier against environmental insults, such
as inhaled cigarette smoke, which is the primary risk factor for the development of chronic …
as inhaled cigarette smoke, which is the primary risk factor for the development of chronic …
Epithelial mesenchymal transition (EMT): a universal process in lung diseases with implications for cystic fibrosis pathophysiology
Cystic Fibrosis (CF) is a genetic disorder that arises due to mutations in the Cystic Fibrosis
Transmembrane Conductance Regulator gene, which encodes for a protein responsible for …
Transmembrane Conductance Regulator gene, which encodes for a protein responsible for …
Epithelial–mesenchymal transition, a spectrum of states: role in lung development, homeostasis, and disease
Epithelial–mesenchymal transition (EMT) plays key roles during lung development and
many lung diseases such as chronic obstructive pulmonary disease (COPD), lung cancer …
many lung diseases such as chronic obstructive pulmonary disease (COPD), lung cancer …
Airway inflammation in chronic obstructive pulmonary disease (COPD): a true paradox
MS Eapen, S Myers, EH Walters… - Expert review of …, 2017 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease (COPD) is primarily an airway
condition, which mainly affects cigarette smokers and presents with shortness of breath that …
condition, which mainly affects cigarette smokers and presents with shortness of breath that …
[HTML][HTML] Phosphodiesterases as therapeutic targets for respiratory diseases
H Zuo, I Cattani-Cavalieri, N Musheshe… - Pharmacology & …, 2019 - Elsevier
Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and
asthma, affect millions of people all over the world. Cyclic adenosine monophosphate …
asthma, affect millions of people all over the world. Cyclic adenosine monophosphate …
Epithelial–Mesenchymal Transition Mechanisms in Chronic Airway Diseases: A Common Process to Target?
A Mottais, L Riberi, A Falco, S Soccal, S Gohy… - International journal of …, 2023 - mdpi.com
Epithelial-to-mesenchymal transition (EMT) is a reversible process, in which epithelial cells
lose their epithelial traits and acquire a mesenchymal phenotype. This transformation has …
lose their epithelial traits and acquire a mesenchymal phenotype. This transformation has …
The effects of epithelial–mesenchymal transitions in COPD induced by cigarette smoke: an update
X Su, W Wu, Z Zhu, X Lin, Y Zeng - Respiratory research, 2022 - Springer
Cigarette smoke is a complex aerosol containing a large number of compounds with a
variety of toxicity and carcinogenicity. Long-term exposure to cigarette smoke significantly …
variety of toxicity and carcinogenicity. Long-term exposure to cigarette smoke significantly …
Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction
Background Small airway fibrosis is the main contributor in airflow obstruction in chronic
obstructive pulmonary disease. Epithelial mesenchymal transition (EMT) has been …
obstructive pulmonary disease. Epithelial mesenchymal transition (EMT) has been …
Mitochondrial alterations during oxidative stress in chronic obstructive pulmonary disease
Y Jiang, X Wang, D Hu - International journal of chronic obstructive …, 2017 - Taylor & Francis
The high incidence of chronic obstructive pulmonary disease (COPD), one of the most
prevalent diseases worldwide, has attracted growing attention. Cigarette smoking is …
prevalent diseases worldwide, has attracted growing attention. Cigarette smoking is …