Pathogenetic mechanisms in the initiation and perpetuation of Sjögren's syndrome

M Voulgarelis, AG Tzioufas - Nature Reviews Rheumatology, 2010 - nature.com
Sjögren's syndrome (SS), a chronic autoimmune disorder, particularly compromises the
function of exocrine glands. The involvement of these glands is characterized by focal …

Transforming growth factor-β and atherosclerosis: interwoven atherogenic and atheroprotective aspects

I Toma, TA McCaffrey - Cell and tissue research, 2012 - Springer
Age-related progression of cardiovascular disease is by far the largest health problem in the
US and involves vascular damage, progressive vascular fibrosis and the accumulation of …

A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs

MF Denny, S Yalavarthi, W Zhao… - The journal of …, 2010 - journals.aai.org
Neutrophil-specific genes are abundant in PBMC microarrays from lupus patients because
of the presence of low-density granulocytes (LDGs) in mononuclear cell fractions. The …

Cardiovascular disease risk burden in primary Sjögren's syndrome: results of a population‐based multicentre cohort study

E Bartoloni, C Baldini, G Schillaci… - Journal of internal …, 2015 - Wiley Online Library
Objective Systemic autoimmune diseases, in particular systemic lupus erythematosus and
rheumatoid arthritis, are characterized by a high risk of premature cardiovascular (CV) …

Endothelial dysfunction in rheumatic autoimmune diseases

G Murdaca, BM Colombo, P Cagnati, R Gulli, F Spanò… - Atherosclerosis, 2012 - Elsevier
Rheumatic autoimmune diseases have been associated with accelerated atherosclerosis
and various types of vasculopathies. Atherosclerosis is an inflammatory condition which …

Systemic inflammation as a risk factor for atherothrombosis

SI van Leuven, R Franssen, JJ Kastelein, M Levi… - …, 2008 - academic.oup.com
Several chronic inflammatory disorders, such as systemic lupus erythematosus (SLE) and
rheumatoid arthritis (RA), and chronic infections that are associated with a chronic …

[HTML][HTML] Risk of subsequent ischemic and hemorrhagic stroke in patients hospitalized for immune-mediated diseases: a nationwide follow-up study from Sweden

B Zöller, X Li, J Sundquist, K Sundquist - BMC neurology, 2012 - Springer
Background Certain immune-mediated diseases (IMDs) have been associated with
increased risk for cardiovascular disorders. The aim of the present study was to examine …

Rheumatic disease and carotid intima-media thickness: a systematic review and meta-analysis

PN Tyrrell, J Beyene, BM Feldman… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—To perform a systematic review and meta-analysis to examine whether
rheumatic disease is associated with an increased carotid intima-media thickness (CIMT; …

[HTML][HTML] Risk of subsequent coronary heart disease in patients hospitalized for immune-mediated diseases: a nationwide follow-up study from Sweden

B Zöller, X Li, J Sundquist, K Sundquist - PloS one, 2012 - journals.plos.org
Background Certain immune-mediated diseases (IMDs), such as rheumatoid arthritis and
systemic lupus erythematosus, have been linked to cardiovascular disorders. We examined …

Anti-dsDNA antibodies increase the cardiovascular risk in systemic lupus erythematosus promoting a distinctive immune and vascular activation

AM Patiño-Trives, C Pérez-Sánchez… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Systemic lupus erythematosus (SLE) is associated to boosted atherosclerosis
development and a higher cardiovascular disease risk. This study aimed to delineate the …