The etiopathogenic mechanisms of schizophrenia are to date unknown, although several
hypotheses have been suggested. Accumulating evidence suggests that excessive free …

Vitamin C (Vit C) is considered to be a vital antioxidant molecule in the brain. Intracellular Vit
C helps maintain integrity and function of several processes in the central nervous system …

Background Schizophrenia is associated with impaired antioxidant defense, including
abnormal serum, plasma, and red blood cell (RBC) oxidative stress parameters. We …

Oxidative stress has been implicated in the pathogenesis of diverse disease states, and may
be a common pathogenic mechanism underlying many major psychiatric disorders, as the …

The pathophysiology of psychiatric diseases, including depression, anxiety, schizophrenia
and autism, is far from being fully elucidated. In recent years, a potential role of the oxidative …

Increasing evidence indicates that oxidative damage exists in schizophrenia. Available
literature about possible mechanisms of oxidative stress induction was reviewed …

Chronic inflammation and oxidative stress have been implicated in the pathophysiology of
Major Depressive Disorder (MDD), as well as in a number of chronic medical conditions …

Major depression is characterized for symptoms at the psychological, behavioral and
physiological levels. The chronic mild stress model has been used as an animal model of …

Oxidative stress is a well-recognized participant in the pathophysiology of multiple brain
disorders, particularly neurodegenerative conditions such as Alzheimer's and Parkinson's …

Various mechanisms involved in schizophrenia pathophysiology, such as dopamine
dysregulation, glutamate/NMDA receptor dysfunction, neuroinflammation or redox …