Lupus nephritis (LN) is an inflammatory condition of the kidneys that encompasses various
patterns of renal disease including glomerular and tubulointerstitial pathology. It is a major …

New insights into the mechanisms of autoimmune diseases have been obtained not only
from preclinical studies, but also from clinical trials of pan-B-cell-directed therapy. Overall …

Objectives To assess the achievability and effect of attaining low disease activity (LDA) or
remission in childhood-onset SLE (cSLE). Methods Attainment of three adult-SLE derived …

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by a
widespread organ involvement. Recent studies have suggested that extra virgin olive oil …

Objectives To identify predictors of low disease activity and clinical remission following
belimumab treatment in SLE. Methods SLE patients who received belimumab 10 mg/kg (N …

Systemic lupus erythematosus (SLE) is considered an autoimmune disease with multiorgan
involvement. Many advances have been made during the last decade regarding …

Monocytes and macrophages are critical effectors and regulators of inflammation and innate
immune response, which appear altered in different autoimmune diseases such as systemic …

The objective of the study was to evaluate prospectively real-life experience on the effect of
belimumab on patients with active systemic lupus erythematosus (SLE). Forty-eight patients …

Summary Background The Definitions Of Remission In Systemic Lupus Erythematosus
(DORIS) international task force has proposed remission definitions that are amenable to …

Humoral autoimmunity is central to the development of systemic lupus erythematosus (SLE).
Complement receptor type 2 (CR2)/CD21 plays a key role in the development of high-affinity …