Focus on the mechanisms and functions of pyroptosis, inflammasomes, and inflammatory caspases in infectious diseases

H Song, B Yang, Y Li, A Qian, Y Kang… - … Medicine and Cellular …, 2022 - Wiley Online Library
Eukaryotic cells can initiate several distinct self‐destruction mechanisms to display essential
roles for the homeostasis maintenance, development, and survival of an organism …

Single Domain Antibody application in bacterial infection diagnosis and neutralization

Q Qin, H Liu, W He, Y Guo, J Zhang, J She… - Frontiers in …, 2022 - frontiersin.org
Increasing antibiotic resistance to bacterial infections causes a serious threat to human
health. Efficient detection and treatment strategies are the keys to preventing and reducing …

The effects of dietary immunostimulants on the innate immune response of Indian major carp: A review

S Kumar, AK Choubey, PK Srivastava - Fish & Shellfish Immunology, 2022 - Elsevier
Immunostimulants, as feed additives, play an important role in maintaining fish health and
enhancing their overall growth by providing resistance against diseases in cultured fish. At …

Integrated analysis of immune parameters, miRNA-mRNA interaction, and immune genes expression in the liver of rainbow trout following infectious hematopoietic …

S Wu, J Huang, Y Li, M Lei, L Zhao, Z Liu - Frontiers in Immunology, 2022 - frontiersin.org
Rainbow trout (Oncorhynchus mykiss) is an important economical cold-water fish worldwide.
However, infection with infectious hematopoietic necrosis virus (IHNV) has severely …

The Biological Functions and Intestinal Inflammation Regulation of IL-21 in Grass Carp (Ctenopharyngodon idella) during Infection with Aeromonas hydrophila

G Yuan, W Zhao, Y Zhang, Z Jia, K Chen, J Wang… - Cells, 2023 - mdpi.com
Interleukin (IL) 21 is a pleiotropic cytokine that plays an important role in regulating innate
and adaptive immune responses. In fish, the biological functions and cell source of IL-21 …

Cyprinid‐specific duplicated membrane TLR5 senses dsRNA as functional homodimeric receptors

Z Liao, C Yang, R Jiang, W Zhu, Y Zhang, J Su - EMBO reports, 2022 - embopress.org
Membrane‐embedded Toll‐like receptor 5 (TLR5) functions as a homodimer to detect
bacterial flagellin. Cyprinid grass carp (Ctenopharyngodon idella) encodes two TLR5 genes …

CRISPR-Cas–induced IRF3 and MAVS knockouts in a salmonid cell line disrupt PRR signaling and affect viral replication

YA van der Wal, H Nordli, A Akandwanaho… - Frontiers in …, 2023 - frontiersin.org
Background Interferon (IFN) responses are critical in the resolution of viral infections and are
actively targeted by many viruses. They also play a role in inducing protective responses …

Integrative mRNA-miRNA interaction analysis associated with the immune response in the head kidney of rainbow trout (Oncorhynchus mykiss) after infectious …

T Sun, J Huang, L Zhu, S Wu, L Zhao, Y Kang - Fish & Shellfish Immunology, 2023 - Elsevier
Rainbow trout (Oncorhynchus mykiss) is an important cold-water fish widely cultivated in
China. The frequent occurrence of viral diseases caused by infectious hematopoietic …

Intelectin enhances the phagocytosis of macrophages via CDC42-WASF2-ARPC2 signaling axis in Megalobrama amblycephala

H Cui, Y Liu, Y Zheng, H Li, M Zhang, X Wang… - International Journal of …, 2023 - Elsevier
Intelectin has been identified in various vertebrates and plays an important role in the host
immune system. In our previous studies, recombinant Megalobrama amblycephala intelectin …

Microbiome analysis of Brazilian women cervix reveals specific bacterial abundance correlation to RIG-like receptor gene expression

AMA Britto, JD Siqueira, G Curty, LR Goes… - Frontiers in …, 2023 - frontiersin.org
The relationship among microbiome, immunity and cervical cancer has been targeted by
several studies, yet many questions remain unanswered. We characterized herein the …