Background Benzodiazepine misuse is a growing public health problem, with increases in
benzodiazepine-related overdose deaths and emergency room visits in recent years …

Benzodiazepines have been in use for over half a century. While they remain highly
prescribed, their unfavorable side-effect profile and abuse liability motivated a search for …

Objective: Persons with opioid use disorder who take benzodiazepines are at high risk for
overdose. The objective of this study was to evaluate the association of benzodiazepine and …

Background Benzodiazepines are a widely prescribed psychoactive drug; in the US, both
medical and nonmedical use of benzodiazepines has increased markedly in the past 15 …

Benzodiazepines (BZDs) are the most widely prescribed drug class in developed countries,
but they have high potential for tolerance, dependence and abuse. Cognitive deficits in long …

Aims Nonmedical prescription sedative/tranquilizer (eg, benzodiazepines) use (NMSTU)
increases risk of overdose when combined with opioids and/or alcohol. Yet, little is known …

Benzodiazepines are widely used drugs for several indications. This study provides, on the
other hand, a global vision of the family starting for their fortuitous discovery, the synthesis of …

The discrepancy between official guidelines and clinical practice is hardly more pronounced
than in the case of benzodiazepines and Z-drugs, also known as benzodiazepine receptor …

Background and Objectives The nonmedical use of benzodiazepines—defined as use
without a prescription or at a dose or frequency higher than prescribed—is increasing …

Benzodiazepines (BZDs) are among the most widely prescribed drugs in developed
countries, but they have a high potential for tolerance, dependence and misuse. High-dose …