From belly to brain: targeting the ghrelin receptor in appetite and food intake regulation

K Howick, BT Griffin, JF Cryan… - International journal of …, 2017 - mdpi.com
Ghrelin is the only known peripherally-derived orexigenic hormone, increasing appetite and
subsequent food intake. The ghrelinergic system has therefore received considerable …

[HTML][HTML] Anti-diabetics and antimicrobials: Harmony of mutual interplay

WAH Hegazy, AAH Rajab, ASA Lila… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Diabetes is one of the four major non-communicable diseases, and appointed by the world
health organization as the seventh leading cause of death worldwide. The scientists have …

Anti-diabetic effects of bioactive peptides: recent advances and clinical implications

C Acquah, CKO Dzuvor, S Tosh… - Critical Reviews in Food …, 2022 - Taylor & Francis
Diabetes mellitus, particularly type 2 diabetes, is a major global health issue, the prevalence
of which seems to be on the rise worldwide. Interventions such as healthy diet, physical …

[HTML][HTML] Ghrelin–physiological functions and regulation

MMI Abdalla - European endocrinology, 2015 - ncbi.nlm.nih.gov
Ghrelin is an orexigenic peptide predominantly secreted from the stomach and stimulates
appetite and growth hormone (GH) release. Studies have provided evidence that ghrelin …

Diazoxide choline extended-release tablet in people with Prader-Willi syndrome: A double-blind, placebo-controlled trial

JL Miller, E Gevers, N Bridges… - The Journal of …, 2023 - academic.oup.com
Abstract Context Prader-Willi syndrome (PWS) is a rare neurobehavioral-metabolic disease
caused by the lack of paternally expressed genes in the chromosome 15q11-q13 region …

The complex world of regulation of pituitary growth hormone secretion: the role of ghrelin, klotho, and nesfatins in it

J Devesa - Frontiers in Endocrinology, 2021 - frontiersin.org
The classic concept of how pituitary GH is regulated by somatostatin and GHRH has
changed in recent years, following the discovery of peripheral hormones involved in the …

Healthy sleep every day keeps the doctor away

CL Feingold, A Smiley - … Journal of Environmental Research and Public …, 2022 - mdpi.com
When one considers the big picture of their health, sufficient sleep may often go overlooked
as a keystone element in this picture. Insufficient sleep in either quality or duration is a …

Ghrelin function in human obesity and type 2 diabetes: a concise review

R Churm, JS Davies, JW Stephens, SL Prior - Obesity Reviews, 2017 - Wiley Online Library
The 28 amino acid hormone, ghrelin, has been found to have various effects on metabolism.
This review will focus on the pathways integrated into ghrelin's effect within the …

Early-stage Alzheimer's disease is associated with simultaneous systemic and central nervous system dysregulation of insulin-linked metabolic pathways

SM de la Monte, M Tong, LA Daiello… - Journal of Alzheimer's …, 2019 - content.iospress.com
Background: Brain insulin resistance is a well-recognized abnormality in Alzheimer's
disease (AD) and the likely mediator of impaired glucose utilization that emerges early and …

Neurotrophic effects of intermittent fasting, calorie restriction and exercise: a review and annotated bibliography

E Mayor - Frontiers in Aging, 2023 - frontiersin.org
In the last decades, important progress has been achieved in the understanding of the
neurotrophic effects of intermittent fasting (IF), calorie restriction (CR) and exercise …