GRP78: A cell's response to stress
Abstract Background Glucose-Regulated Protein 78 (GRP78) is a chaperone heat shock
protein that has been intensely studied in the last two decades. GRP78 is the master of the …
protein that has been intensely studied in the last two decades. GRP78 is the master of the …
The role of extracellular vesicles in COVID-19 virus infection
M Hassanpour, J Rezaie, M Nouri, Y Panahi - Infection, Genetics and …, 2020 - Elsevier
Extracellular vesicles releasing from various types of cells contribute to intercellular
communication via delivering bio-molecules like nucleic acids, proteins, and lipids to …
communication via delivering bio-molecules like nucleic acids, proteins, and lipids to …
TMPRSS2 expression dictates the entry route used by SARS‐CoV‐2 to infect host cells
J Koch, ZM Uckeley, P Doldan, M Stanifer… - The EMBO …, 2021 - embopress.org
SARS‐CoV‐2 is a newly emerged coronavirus that caused the global COVID‐19 outbreak in
early 2020. COVID‐19 is primarily associated with lung injury, but many other clinical …
early 2020. COVID‐19 is primarily associated with lung injury, but many other clinical …
Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks
WM Schneider, JM Luna, HH Hoffmann… - Cell, 2021 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic has claimed the lives of
over one million people worldwide. The causative agent, severe acute respiratory syndrome …
over one million people worldwide. The causative agent, severe acute respiratory syndrome …
Structural insights into coronavirus entry
MA Tortorici, D Veesler - Advances in virus research, 2019 - Elsevier
Coronaviruses (CoVs) have caused outbreaks of deadly pneumonia in humans since the
beginning of the 21st century. The severe acute respiratory syndrome coronavirus (SARS …
beginning of the 21st century. The severe acute respiratory syndrome coronavirus (SARS …
A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike
S Xia, L Yan, W Xu, AS Agrawal, A Algaissi… - Science …, 2019 - science.org
Continuously emerging highly pathogenic human coronaviruses (HCoVs) remain a major
threat to human health, as illustrated in past SARS-CoV and MERS-CoV outbreaks. The …
threat to human health, as illustrated in past SARS-CoV and MERS-CoV outbreaks. The …
The MERS-CoV receptor DPP4 as a candidate binding target of the SARS-CoV-2 spike
Y Li, Z Zhang, L Yang, X Lian, Y Xie, S Li, S Xin, P Cao… - Iscience, 2020 - cell.com
The ongoing outbreak of the novel coronavirus pneumonia COVID-19 has caused great
number of cases and deaths, but our understanding about the pathogen SARS-CoV-2 …
number of cases and deaths, but our understanding about the pathogen SARS-CoV-2 …
Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors
Abstract The Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe and
often lethal respiratory illness in humans, and no vaccines or specific treatments are …
often lethal respiratory illness in humans, and no vaccines or specific treatments are …
[HTML][HTML] Physiological and molecular triggers for SARS-CoV membrane fusion and entry into host cells
JK Millet, GR Whittaker - Virology, 2018 - Elsevier
During viral entry, enveloped viruses require the fusion of their lipid envelope with host cell
membranes. For coronaviruses, this critical step is governed by the virally-encoded spike (S) …
membranes. For coronaviruses, this critical step is governed by the virally-encoded spike (S) …
Trypsin treatment unlocks barrier for zoonotic bat coronavirus infection
VD Menachery, KH Dinnon III, BL Yount Jr… - Journal of …, 2020 - Am Soc Microbiol
Traditionally, the emergence of coronaviruses (CoVs) has been attributed to a gain in
receptor binding in a new host. Our previous work with severe acute respiratory syndrome …
receptor binding in a new host. Our previous work with severe acute respiratory syndrome …