Reactive oxygen species (ROS) induce carcinogenesis by causing genetic mutations,
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …

Mitogen-activated protein (MAP) kinases are a central component in signaling networks in a
multitude of mammalian cell types. This review covers recent advances on specific functions …

摘要背景目前认为在2 型糖尿病的发病机制中缺乏对活性氧(reactive oxygen species, ROS)
的防御作用非常重要; 因此, 编码抗氧化防御酶基因可能会影响疾病的易感性 …

Fipronil (FIP) is widely used across the world as a broad-spectrum phenylpyrazole
insecticide and veterinary drug. FIP was the insecticide to act by targeting the γ-aminobutyric …

Fipronil is a phenylpyrazole insecticide used in various agricultural, horticulture, and
veterinary practices. Besides its wide range of applications, it also causes severe health …

Mycotoxin-induced liver injury is often accompanied by oxidative stress (OS) and
inflammation. This research aimed to explore the potential mechanism of sodium butyrate …

Abstract Parkinson's disease (PD), a common neurodegenerative disease, is typically
associated with the loss of dopaminergic neuron in the substantia nigra pars compacta …

Thousands of tons of neonicotinoids are widely used around the world as broad-spectrum
systemic insecticides and veterinary drugs. Researchers originally thought that …

A wide variety of cell death mechanisms, such as ferroptosis, have been proposed in
mammalian cells, and the classification of cell death attracts global attention because each …

Introduction: Prolonged inflammatory response contributes to the pathogenesis of chronic
disease-related disturbances. Among nuclear receptors (NRs), the orphan NR4A subfamily …