Recent advances in the chemistry of 1, 2, 4-triazoles: Synthesis, reactivity and biological activities
Triazoles are important heterocyclic motifs that are widely found in molecular architectures
with medicinal and pharmaceutical properties. Considering the importance of these …
with medicinal and pharmaceutical properties. Considering the importance of these …
Fused bicyclic 1, 2, 4‐triazoles with one extra sulfur atom: Synthesis, properties, and biological activity
Abstract Fused heterocyclic systems with 1, 2, 4‐triazole scaffold arouse great interest from
researchers in the branch of heterocyclic and medical chemistry because of their wide …
researchers in the branch of heterocyclic and medical chemistry because of their wide …
Synthesis, Structural Characterization, and Antibacterial and Antifungal Activities of Novel 1,2,4-Triazole Thioether and Thiazolo[3,2-b]-1,2,4-triazole Derivatives …
M Ding, S Wan, N Wu, Y Yan, J Li… - Journal of Agricultural and …, 2021 - ACS Publications
A total of 52 novel 1, 2, 4-triazole thioether and thiazolo [3, 2-b]-1, 2, 4-triazole derivatives
bearing the 6-fluoroquinazolinyl moiety were designed, synthesized, and evaluated as …
bearing the 6-fluoroquinazolinyl moiety were designed, synthesized, and evaluated as …
Synthesis, Characterization and In Vitro Evaluation of Novel 5-Ene-thiazolo[3,2-b][1,2,4]triazole-6(5H)-ones as Possible Anticancer Agents
The present paper is devoted to the search for drug-like molecules with anticancer
properties using the thiazolo [3, 2-b][1, 2, 4] triazole-6-one scaffold. A series of 24 novel …
properties using the thiazolo [3, 2-b][1, 2, 4] triazole-6-one scaffold. A series of 24 novel …
Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors
Two series of 20 novel heterocyclic compounds, imidazothiadiazoles (3a-3j) and
thiazolotriazoles (4a-4j) bearing benzenesulfonamide moiety were synthesized in order to …
thiazolotriazoles (4a-4j) bearing benzenesulfonamide moiety were synthesized in order to …
[1,3]Thiazolo[3,2-b][1,2,4]triazol-7-ium salts: synthesis, properties and structural studies
Abstract The reactions of [1, 3] thiazolo [3, 2-b][1, 2, 4] triazol-7-ium salts with nucleophiles
were investigated. Theoretical investigation of reactivity descriptors and structural …
were investigated. Theoretical investigation of reactivity descriptors and structural …
Recent progress in the synthesis of thiazolo[3,2-b][1,2,4]triazoles (microreview)
A summary of the most recent approaches toward synthesis of thiazolo [3, 2-b][1, 2, 4]
triazole system is reported. The microreview covers the latest selected examples on the …
triazole system is reported. The microreview covers the latest selected examples on the …
Synthesis and Antimicrobial Activity of Functional Derivatives of thiazolo [2, 3-c][1, 2, 4] triazoles
Background: Condensed triazoles are a well-known class of heterocyclic compounds due to
a wide range of biological activities. The study is dedicated to the evaluation of the …
a wide range of biological activities. The study is dedicated to the evaluation of the …
1, 2, 4-Triazole derivatives in medicine and pharmacy and application prospects
Y Sameliuk, T Kaplaushenko… - Journal of Faculty of …, 2021 - dergipark.org.tr
Objective: Development of methods for the synthesis, studies of chemical, physico-chemical
and biological properties of 1, 2, 4-triazole derivatives, in particular compounds with …
and biological properties of 1, 2, 4-triazole derivatives, in particular compounds with …
Synthesis, fluorescence properties of novel thiazolo [3, 2-b][1, 2, 4] triazol derivatives as potent SHP2 inhibitors and its uses in sensing for Fe3+ and cell imaging
X Yan, C Zhang, LX Gao, ZT Cao, SY Gan, J Li… - Journal of Molecular …, 2024 - Elsevier
Abstract A series of thiazolo [3, 2-b][1, 2, 4] triazole derivatives containing salicylic acid
fragment were designed and synthesized. Then, their optical properties and biological …
fragment were designed and synthesized. Then, their optical properties and biological …