Recent advances in the chemistry of 1, 2, 4-triazoles: Synthesis, reactivity and biological activities

A Abdelli, S Azzouni, R Plais, A Gaucher, ML Efrit… - Tetrahedron …, 2021 - Elsevier
Triazoles are important heterocyclic motifs that are widely found in molecular architectures
with medicinal and pharmaceutical properties. Considering the importance of these …

Fused bicyclic 1, 2, 4‐triazoles with one extra sulfur atom: Synthesis, properties, and biological activity

MV Slivka, NI Korol, MM Fizer - Journal of Heterocyclic …, 2020 - Wiley Online Library
Abstract Fused heterocyclic systems with 1, 2, 4‐triazole scaffold arouse great interest from
researchers in the branch of heterocyclic and medical chemistry because of their wide …

Synthesis, Structural Characterization, and Antibacterial and Antifungal Activities of Novel 1,2,4-Triazole Thioether and Thiazolo[3,2-b]-1,2,4-triazole Derivatives …

M Ding, S Wan, N Wu, Y Yan, J Li… - Journal of Agricultural and …, 2021 - ACS Publications
A total of 52 novel 1, 2, 4-triazole thioether and thiazolo [3, 2-b]-1, 2, 4-triazole derivatives
bearing the 6-fluoroquinazolinyl moiety were designed, synthesized, and evaluated as …

Synthesis, Characterization and In Vitro Evaluation of Novel 5-Ene-thiazolo[3,2-b][1,2,4]triazole-6(5H)-ones as Possible Anticancer Agents

S Holota, S Komykhov, S Sysak, A Gzella, A Cherkas… - Molecules, 2021 - mdpi.com
The present paper is devoted to the search for drug-like molecules with anticancer
properties using the thiazolo [3, 2-b][1, 2, 4] triazole-6-one scaffold. A series of 24 novel …

Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors

R Kumar, S Bua, S Ram, S Del Prete… - Bioorganic & Medicinal …, 2017 - Elsevier
Two series of 20 novel heterocyclic compounds, imidazothiadiazoles (3a-3j) and
thiazolotriazoles (4a-4j) bearing benzenesulfonamide moiety were synthesized in order to …

[1,3]Thiazolo[3,2-b][1,2,4]triazol-7-ium salts: synthesis, properties and structural studies

M Slivka, N Korol, M Fizer, V Baumer… - Heterocyclic …, 2018 - degruyter.com
Abstract The reactions of [1, 3] thiazolo [3, 2-b][1, 2, 4] triazol-7-ium salts with nucleophiles
were investigated. Theoretical investigation of reactivity descriptors and structural …

Recent progress in the synthesis of thiazolo[3,2-b][1,2,4]triazoles (microreview)

NI Korol, MV Slivka - Chemistry of Heterocyclic Compounds, 2017 - Springer
A summary of the most recent approaches toward synthesis of thiazolo [3, 2-b][1, 2, 4]
triazole system is reported. The microreview covers the latest selected examples on the …

Synthesis and Antimicrobial Activity of Functional Derivatives of thiazolo [2, 3-c][1, 2, 4] triazoles

M Slivka, M Fizer, R Mariychuk… - Letters in Drug …, 2022 - ingentaconnect.com
Background: Condensed triazoles are a well-known class of heterocyclic compounds due to
a wide range of biological activities. The study is dedicated to the evaluation of the …

1, 2, 4-Triazole derivatives in medicine and pharmacy and application prospects

Y Sameliuk, T Kaplaushenko… - Journal of Faculty of …, 2021 - dergipark.org.tr
Objective: Development of methods for the synthesis, studies of chemical, physico-chemical
and biological properties of 1, 2, 4-triazole derivatives, in particular compounds with …

Synthesis, fluorescence properties of novel thiazolo [3, 2-b][1, 2, 4] triazol derivatives as potent SHP2 inhibitors and its uses in sensing for Fe3+ and cell imaging

X Yan, C Zhang, LX Gao, ZT Cao, SY Gan, J Li… - Journal of Molecular …, 2024 - Elsevier
Abstract A series of thiazolo [3, 2-b][1, 2, 4] triazole derivatives containing salicylic acid
fragment were designed and synthesized. Then, their optical properties and biological …