Various pharmacological effects for Portulaca oleracea were shown in previous studies.
Therefore, the effects of P. oleracea and its derivatives on respiratory, allergic, and …

Nephrotoxicity is a very important complication of 5-fluorouracil (5-FU)–treated cancer
patients. Increased oxidative stress, kidney damage, and apoptosis play an important role in …

Objective (s): 5-fluorouracil-induced (5-FU), an anticarcinogenic agent, is reported to have
side-effects that include hepatotoxicity and nephrotoxicity. The study objective was to …

The renin-angiotensin-aldosterone system is a physiological system that plays an important
role in the regulation of blood pressure and body water-electrolyte balance, in which the …

Objective: To explore the possible effects of naringin on acrylamide-induced nephrotoxicity
in rats. Methods: Sprague-Dawley rats weighing 200-250 g were randomly divided into five …

This study assessed the preventive properties of naringin and naringenin on paclitaxel‐
induced nephrotoxicity and cardiotoxicity in adult male Wistar rats. Intraperitoneal injection …

The ubiquitous use of diazinon (DZN, an organophosphorus insecticide) has increased the
probability of occupational, public, and the ecosystem exposure; these exposures are linked …

Objective To investigate the effects of quercetin (Q) and rutin on 5-fluorouracil (5-FU)-
induced hepatotoxicity. Methods The control group was corn oil. The 5-FU group rats were …

Background The use of cyclophosphamide (CP) as a chemotherapeutic agent is limited by
its major complication haemorrhagic cystitis (HC). Finding preventive, safe, and efficient …

Herbacetin (HBN) is a glycosylated flavonoid, which possesses numerous pharmacological
properties. Cyclophosphamide (CYC) is a chemotherapeutic drug that adversely affects the …