The risks of long-term use of proton pump inhibitors: a critical review

M Jaynes, AB Kumar - Therapeutic advances in drug safety, 2019 - journals.sagepub.com
Proton pump inhibitors (PPIs) are among the most frequently prescribed medications. Their
use is likely even higher than estimated due to an increase in the number of PPIs available …

Mechanisms of proton pump inhibitor‐induced hypomagnesemia

LMM Gommers, JGJ Hoenderop… - Acta …, 2022 - Wiley Online Library
Proton pump inhibitors (PPIs) reliably suppress gastric acid secretion and are therefore the
first‐line treatment for gastric acid‐related disorders. Hypomagnesemia (serum magnesium …

The Rotterdam Study: 2018 update on objectives, design and main results

MA Ikram, GGO Brusselle, SD Murad… - European journal of …, 2017 - Springer
Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

Proton pump inhibitors and risk of incident CKD and progression to ESRD

Y Xie, B Bowe, T Li, H Xian… - Journal of the …, 2016 - journals.lww.com
The association between proton pump inhibitors (PPI) use and risk of acute interstitial
nephritis has been described. However, whether exposure to PPI associates with incident …

[HTML][HTML] Risk of death among users of proton pump inhibitors: a longitudinal observational cohort study of United States veterans

Y Xie, B Bowe, T Li, H Xian, Y Yan, Z Al-Aly - BMJ open, 2017 - bmjopen.bmj.com
Objective Proton pump inhibitors (PPIs) are widely used, and their use is associated with
increased risk of adverse events. However, whether PPI use is associated with excess risk of …

Hypomagnesemia and hypermagnesemia

S Van Laecke - Acta Clinica Belgica, 2019 - Taylor & Francis
Introduction: Magnesium is an essential element which also has pleiotropic effects in
humans. Recent studies have altered our interpretation of a disturbed magnesium balance …

Proton pump inhibitors and hypomagnesemia: A meta-analysis of observational studies

T Srinutta, A Chewcharat, K Takkavatakarn… - Medicine, 2019 - journals.lww.com
Background: Previous meta-analyses have suggested that there might be an association
between the use of proton pump inhibitors (PPIs) and the development of hypomagnesemia …

Proton pump inhibitors and the kidney: implications of current evidence for clinical practice and when and how to deprescribe

Z Al-Aly, G Maddukuri, Y Xie - American Journal of Kidney Diseases, 2020 - Elsevier
Proton pump inhibitors (PPIs), long thought to be safe, are associated with a number of
nonkidney adverse health outcomes and several untoward kidney outcomes, including …

[HTML][HTML] Essential nutrient interactions: does low or suboptimal magnesium status interact with vitamin D and/or calcium status?

A Rosanoff, Q Dai, SA Shapses - Advances in nutrition, 2016 - Elsevier
Although much is known about magnesium, its interactions with calcium and vitamin D are
less well studied. Magnesium intake is low in populations who consume modern processed …

Magnesium in pregnancy

LM Dalton, DM Ní Fhloinn, GT Gaydadzhieva… - Nutrition …, 2016 - academic.oup.com
Magnesium deficiency is prevalent in women of childbearing age in both developing and
developed countries. The need for magnesium increases during pregnancy, and the …