Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs
Metabotropic glutamate (mGlu) receptors have been considered as potential targets for
neuroprotective drugs, but the lack of specific drugs has limited the development of …
neuroprotective drugs, but the lack of specific drugs has limited the development of …
Swimming training prevents pentylenetetrazol‐induced inhibition of Na+, K+‐ATPase activity, seizures, and oxidative stress
Purpose: In the present study we decided to investigate whether physical exercise protects
against the electrographic, oxidative, and neurochemical alterations induced by …
against the electrographic, oxidative, and neurochemical alterations induced by …
Maternal epileptic seizure induced by Pentylenetetrazol: Apoptotic neurodegeneration and decreased GABAB1 receptor expression in prenatal rat brain
Epilepsy is a prominent sign of neurological dysfunction in children with various fetal and
maternal deficiencies. However, the detailed mechanism and influences underlying epileptic …
maternal deficiencies. However, the detailed mechanism and influences underlying epileptic …
Effect of pentylenetetrazol-induced epileptic seizure on thiol redox state in the mouse cerebral cortex
N Patsoukis, G Zervoudakis, CD Georgiou… - Epilepsy research, 2004 - Elsevier
In the present study we examined the effects of pentylenetetrazol (PTZ) administration on the
thiol redox state (TRS), lipid peroxidation and protein oxidation in left and right mouse …
thiol redox state (TRS), lipid peroxidation and protein oxidation in left and right mouse …
Thiol Redox State and Lipid and Protein Oxidation in the Mouse Striatum after Pentylenetetrazol‐induced Epileptic Seizure
N Patsoukis, G Zervoudakis, CD Georgiou… - …, 2005 - Wiley Online Library
Purpose: In the present study, we examined the effects of pentylenetetrazol (PTZ)
administration on the thiol redox state (TRS), lipid peroxidation, and protein oxidation in the …
administration on the thiol redox state (TRS), lipid peroxidation, and protein oxidation in the …
Investigation of the effects of tianeptine and fluoxetine on pentylenetetrazole-induced seizures in rats
The effects of tianeptine and fluoxetine on pentylenetetrazole (PTZ)-induced seizures in rats
were investigated. Female Wistar rats (172–278 g) were used in the study. Tianeptine (1.25 …
were investigated. Female Wistar rats (172–278 g) were used in the study. Tianeptine (1.25 …
Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R, S)-4-phosphonophenylglycine
J Folbergrová, R Haugvicová, P Mareš - Experimental neurology, 2003 - Elsevier
The potential anticonvulsant effect of group III metabotropic glutamate receptor (mGluR)
agonist (R, S)-4-phosphonophenylglycine ((R, S)-PPG) against seizures induced in …
agonist (R, S)-4-phosphonophenylglycine ((R, S)-PPG) against seizures induced in …
Ethanol and PTZ effects on siRNA‐mediated GABAB1 receptor: Down regulation of intracellular signaling pathway in prenatal rat cortical and hippocampal neurons
GABAB receptors (R) are widely expressed and distributed in the nervous system, and have
been implicated in variety of neurodegenerative and pathophysiological disorders …
been implicated in variety of neurodegenerative and pathophysiological disorders …
Diphenyl diselenide and 2, 3-dimercaptopropanol increase the PTZ-induced chemical seizure and mortality in mice
VB Brito, V Folmer, GO Puntel, R Fachinetto… - Brain research …, 2006 - Elsevier
The aim of the present study was to evaluate the interaction between a classic GABAergic
antagonist—pentylenetetrazol (PTZ) with an organoselenium compound—diphenyl …
antagonist—pentylenetetrazol (PTZ) with an organoselenium compound—diphenyl …
Avaliação dos efeitos centrais e antinociceptivos das frações isoladas da raiz de Petiveria alliacea L.(TIPI) em camundongos
PB Gomes - 2006 - repositorio.ufc.br
UNIVERSIDADE FEDERAL DO CEARÁ FACULDADE DE MEDICINA DEPARTAMENTO DE
FISIOLOGIA E FARMACOLOGIA CURSO DE PÓS-GRADUAÇÃO EM FARM Page 1 i …
FISIOLOGIA E FARMACOLOGIA CURSO DE PÓS-GRADUAÇÃO EM FARM Page 1 i …