The current view is that breast cancer is a stem cell disease characterized by the existence
of cancer cells with stem-like features and tumor-initiating potential. These cells are made …

The ovarian steroid hormone progesterone and its nuclear receptor, the Progesterone
Receptor (PR), play an essential role in the regulation of cell proliferation and differentiation …

BACKGROUND Breast cancer is a common malignant tumor that seriously threatens
women's health. Breast cancer stem cell (CSC)-like cell population may be the main factor …

Abstract Purpose of Review This review will discuss how the steroid hormones, estrogen
and progesterone, as well as treatments that target steroid receptors, can regulate cancer …

Long non-coding RNAs (lncRNAs) are emerging as important players in regulation of gene
expression in higher eukaryotes. DDX5/p68 RNA helicase protein which is involved in …

Although hormone therapy is widely used by millions of women to relieve symptoms of
menopause, it has been associated with several side-effects such as coronary heart …

Objective: The aim of the study was to review the role of hormone therapy in menopausal
patients with breast cancer and gynecologic malignancies. Methods: We searched …

Medroxyprogesterone acetate (MPA) is a first generation progestin that has been in clinical
use for various hormonal conditions in women since the 1960s. Although developed as a …

Recent attention has focused on the development of an effective three-dimensional (3D) cell
culture system enabling the rapid enrichment of cancer stem cells (CSCs) that are resistant …

Cancer stem cells (CSCs) represent a small subset of heterogeneous cells within tumors
that possess the ability to self-renew and initiate tumorigenesis. They serve as potential …