The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?
Different animal models of pulmonary fibrosis have been developed to investigate potential
therapies for idiopathic pulmonary fibrosis (IPF). The most common is the bleomycin model …
therapies for idiopathic pulmonary fibrosis (IPF). The most common is the bleomycin model …
Molecular targets in pulmonary fibrosis: the myofibroblast in focus
CJ Scotton, RC Chambers - Chest, 2007 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is one of a group of interstitial lung diseases that are
characterized by excessive matrix deposition and destruction of the normal lung …
characterized by excessive matrix deposition and destruction of the normal lung …
An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management
G Raghu, HR Collard, JJ Egan, FJ Martinez… - American journal of …, 2011 - atsjournals.org
This document is an international evidence-based guideline on the diagnosis and
management of idiopathic pulmonary fibrosis, and is a collaborative effort of the American …
management of idiopathic pulmonary fibrosis, and is a collaborative effort of the American …
Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial
Background Idiopathic pulmonary fibrosis is a fatal disease for which no effective treatment
exists. We assessed whether treatment with interferon gamma-1b improved survival …
exists. We assessed whether treatment with interferon gamma-1b improved survival …
A multicenter, prospective, randomized, double‐blind, placebo‐controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for …
RK Hoyles, RW Ellis, J Wellsbury… - … : Official Journal of …, 2006 - Wiley Online Library
Objective The lack of randomized controlled trials (RCTs) in pulmonary fibrosis in systemic
sclerosis (SSc) has hampered an evidence‐based approach to treatment. This RCT was …
sclerosis (SSc) has hampered an evidence‐based approach to treatment. This RCT was …
Thoracic manifestations of rheumatoid arthritis
AJ Esposito, SG Chu, R Madan… - Clinics in chest …, 2019 - chestmed.theclinics.com
Rheumatoid arthritis (RA) is a destructive, systemic, inflammatory disorder that
characteristically affects small, diarthrodial joints in a progressive, symmetric, and erosive …
characteristically affects small, diarthrodial joints in a progressive, symmetric, and erosive …
Medical treatments for idiopathic pulmonary fibrosis: a systematic review and network meta-analysis
Background Idiopathic pulmonary fibrosis (IPF) is a respiratory disorder with a poor
prognosis. Our objective is to assess the comparative effectiveness of 22 approved or …
prognosis. Our objective is to assess the comparative effectiveness of 22 approved or …
Strategies for treating idiopathic pulmonary fibrosis
RM Du Bois - Nature reviews Drug discovery, 2010 - nature.com
Idiopathic pulmonary fibrosis (IPF) is the most common and most lethal diffuse fibrosing lung
disease, with a mortality rate that exceeds that of many cancers. Recently, there have been …
disease, with a mortality rate that exceeds that of many cancers. Recently, there have been …
Colchicine in clinical medicine. A guide for internists
G Cocco, DCC Chu, S Pandolfi - European journal of internal medicine, 2010 - Elsevier
Colchicine (COL) has been used in medicine for a long time. It is well recognized as a valid
therapy in acute flares of gouty arthritis, familial Mediterranean fever (FMF), Behçet's …
therapy in acute flares of gouty arthritis, familial Mediterranean fever (FMF), Behçet's …