The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

A Moeller, K Ask, D Warburton, J Gauldie… - The international journal …, 2008 - Elsevier
Different animal models of pulmonary fibrosis have been developed to investigate potential
therapies for idiopathic pulmonary fibrosis (IPF). The most common is the bleomycin model …

Molecular targets in pulmonary fibrosis: the myofibroblast in focus

CJ Scotton, RC Chambers - Chest, 2007 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is one of a group of interstitial lung diseases that are
characterized by excessive matrix deposition and destruction of the normal lung …

An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management

G Raghu, HR Collard, JJ Egan, FJ Martinez… - American journal of …, 2011 - atsjournals.org
This document is an international evidence-based guideline on the diagnosis and
management of idiopathic pulmonary fibrosis, and is a collaborative effort of the American …

Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial

TE King, C Albera, WZ Bradford, U Costabel, P Hormel… - The Lancet, 2009 - thelancet.com
Background Idiopathic pulmonary fibrosis is a fatal disease for which no effective treatment
exists. We assessed whether treatment with interferon gamma-1b improved survival …

A multicenter, prospective, randomized, double‐blind, placebo‐controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for …

RK Hoyles, RW Ellis, J Wellsbury… - … : Official Journal of …, 2006 - Wiley Online Library
Objective The lack of randomized controlled trials (RCTs) in pulmonary fibrosis in systemic
sclerosis (SSc) has hampered an evidence‐based approach to treatment. This RCT was …

Thoracic manifestations of rheumatoid arthritis

AJ Esposito, SG Chu, R Madan… - Clinics in chest …, 2019 - chestmed.theclinics.com
Rheumatoid arthritis (RA) is a destructive, systemic, inflammatory disorder that
characteristically affects small, diarthrodial joints in a progressive, symmetric, and erosive …

Medical treatments for idiopathic pulmonary fibrosis: a systematic review and network meta-analysis

T Pitre, J Mah, W Helmeczi, MF Khalid, S Cui, M Zhang… - Thorax, 2022 - thorax.bmj.com
Background Idiopathic pulmonary fibrosis (IPF) is a respiratory disorder with a poor
prognosis. Our objective is to assess the comparative effectiveness of 22 approved or …

Strategies for treating idiopathic pulmonary fibrosis

RM Du Bois - Nature reviews Drug discovery, 2010 - nature.com
Idiopathic pulmonary fibrosis (IPF) is the most common and most lethal diffuse fibrosing lung
disease, with a mortality rate that exceeds that of many cancers. Recently, there have been …

Colchicine in clinical medicine. A guide for internists

G Cocco, DCC Chu, S Pandolfi - European journal of internal medicine, 2010 - Elsevier
Colchicine (COL) has been used in medicine for a long time. It is well recognized as a valid
therapy in acute flares of gouty arthritis, familial Mediterranean fever (FMF), Behçet's …

Interstitial lung disease guideline

AU Wells, N Hirani - Thorax, 2008 - thorax.bmj.com
1. INTRODUCTION 1.1 An overview of the ILD guideline Since the publication of the first
BTS guidelines for diffuse lung disease nearly 10years ago, 1 the specialty has seen …