The metabolic syndrome, a human disease

M Alemany - International journal of molecular sciences, 2024 - mdpi.com
This review focuses on the question of metabolic syndrome (MS) being a complex, but
essentially monophyletic, galaxy of associated diseases/disorders, or just a syndrome of …

Subcellular one carbon metabolism in cancer, aging and epigenetics

T Bernasocchi, R Mostoslavsky - Frontiers in epigenetics and …, 2024 - frontiersin.org
The crosstalk between metabolism and epigenetics is an emerging field that is gaining
importance in different areas such as cancer and aging, where changes in metabolism …

Di (2-ethylhexyl) phthalate induces reproductive toxicity and transgenerational reproductive aging in Caenorhabditis elegans

Y Zhang, J Li, W Shi, L Lu, Q Zhou, H Zhang, R Liu… - Environmental …, 2023 - Elsevier
With the large-scale production and use of plastic products, the global plastic pollution
problem is becoming more and more serious. The plasticizer di (2-ethylhexyl) phthalate …

Exposure to Chinese famine in early life and height across 2 generations: a longitudinal study based on the China Health and Nutrition Survey

WY Yao, YF Yu, L Li, WH Xu - The American Journal of Clinical Nutrition, 2024 - Elsevier
Background Poor nutrition early in life is associated with short stature, which is associated
with increased risk of cardiovascular disease and mortality in later life. Less evidence is …

TIGAR exacerbates obesity by triggering LRRK2-mediated defects in macroautophagy and chaperone-mediated autophagy in adipocytes

T Zhang, KG Linghu, J Tan, M Wang, D Chen, Y Shen… - Autophagy, 2024 - Taylor & Francis
Obesity is one of the most common metabolic diseases around the world, which is
distinguished by the abnormal buildup of triglycerides within adipose cells. Recent research …

Association between early exposure to famine and risk of renal impairment in adulthood: a systematic review and meta-analysis

M Huang, X Zeng, Z Dai, Y Huang, C Luo, X Tan… - Nutrition & …, 2024 - nature.com
Malnutrition early in life increases the later-life risk of noncommunicable diseases, and
previous epidemiologic studies have found a link between famine and renal impairment, but …

A bibliometric and visualization analysis of global research status and frontiers on autophagy in cardiomyopathies from 2004 to 2023

X Zeng, B Shu, Q Zeng, X Wang, K Li… - International Journal of …, 2024 - journals.lww.com
Background: Autophagy is intimately associated with the development of cardiomyopathy
and has received widespread attention in recent years. However, no relevant bibliometric …

Quercetin ameliorates oxidative stress-induced apoptosis of granulosa cells in dairy cow follicular cysts by activating autophagy via the SIRT1/ROS/AMPK signaling …

H Duan, F Wang, K Wang, S Yang, R Zhang… - Journal of Animal …, 2024 - Springer
Background Follicular cysts contribute significantly to reproductive loss in high-yield dairy
cows. This results from the death of follicular granulosa cells (GCs) caused by oxidative …

Longevity extension in rats via improved redox homeostasis with high carbohydrate diet intervention from weaning to adulthood: a comprehensive multi-omics study

Y Dong, Q Zhu, Y Li, R Wang, W Xu, X Tang, X Li… - Food & Function, 2024 - pubs.rsc.org
Early dietary patterns potentially influence the health status and lifespan throughout
adulthood and the entire lifespan. However, dietary behaviors are difficult for everyone to …

Epigenome-wide association study of systemic effects of obesity susceptibility in human twins

GE Duncan, A Avery, MB Maamar, EE Nilsson… - Epigenetics, 2023 - Taylor & Francis
The current study was designed to use an epigenome-wide association approach (EWAS) to
identify potential systemic DNA methylation alterations that are associated with obesity using …